Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial.

Slides:

Advertisements

Similar presentations

Lost in translation The Journal of Thoracic and Cardiovascular Surgery

Advertisements

Manuel J. Antunes, MD, PhD, DSc

A wolf in sheep's clothing

Mycoplasma hominis prosthetic valve endocarditis: The value of molecular sequencing in cardiac surgery Syed T. Hussain, MD, Steven M. Gordon, MD, Carmela.

New engineering treatment of bovine pericardium confers outstanding resistance to calcification in mitral and pulmonary implantations in a juvenile sheep.

Biodegradable polymer with collagen microsponge serves as a new bioengineered cardiovascular prosthesis Shigemitsu Iwai, MD, Yoshiki Sawa, MD, Hajime.

Tracheal regeneration: Myth or fact?

A novel method to reduce pericardial adhesion: A combination technique with hyaluronic acid biocompatible membrane Yuji Naito, MD, Toshiharu Shin'oka,

Aortic root replacement with a novel decellularized cryopreserved aortic homograft: Postoperative immunoreactivity and early results Kenton J. Zehr,

Wen-Jian Jiang, MD, Jin-Hua Li, MD, Jiang Dai, MD, Yong-Qiang Lai, MD

Expanding options to manage traumatic thoracic vascular injuries

Reconstruction of the right ventricular outflow tract with a bovine jugular vein graft fixed with a naturally occurring crosslinking agent (genipin) in.

Behavior of vital and killed autologous pericardium in the descending aorta of sheep David T. Cheung, PhD, Suk Jung Choo, MD, Albert C. Grobe, MS, Douglas.

Electromechanical characterization of a tissue-engineered myocardial patch derived from extracellular matrix Takeyoshi Ota, MD, PhD, Thomas W. Gilbert,

Building a bioartificial heart: A 3-song saga

Spontaneous regression of a mediastinal thymoma

Intrinsic cardiac stem cells are essential for regeneration

First human transplantation of a bioengineered airway tissue

Victor van Berkel, MD, PhD

Paclitaxel coating of the luminal surface of hemodialysis grafts with effective suppression of neointimal hyperplasia Insu Baek, MS, Cheng Zhe Bai, PhD,

William M. DeCampli, MD, PhD

Go on-pump or off-pump in diabetic patients?

Recombinant human hepatocyte growth factor transfection alleviates hyperkinetic pulmonary artery hypertension in rabbit models Wei Wang, MD, Kai Liu,

The lord of the rings Antonio Miceli, MD, PhD

Tissue regeneration observed in a basic fibroblast growth factor–loaded porous acellular bovine pericardium populated with mesenchymal stem cells Yen.

Yang Zhang, MD, Haiquan Chen, MD, PhD

Loss of CRNN expression is associated with advanced tumor stage and poor survival in patients with esophageal squamous cell carcinoma Po-Kuei Hsu, MD,

In situ tissue regeneration using a novel tissue-engineered, small-caliber vascular graft without cell seeding Takenori Yokota, MD, Hajime Ichikawa,

Dacron inhibition of arterial regenerative activities

Occult active giant cell aortitis necessitating surgical repair

Reduced membranous β-catenin protein expression is associated with metastasis and poor prognosis in squamous cell carcinoma of the esophagus Po-Kuei.

Pathologic features of cryopreserved aortic allograft implanted in the active infection Akitoshi Yamada, MD, Kenji Okada, MD, Rei Takahashi, MD, Yutaka.

Innovation and science: The future of valve design

It's not “just a shunt” but sometimes it should be…

Fixing the supply problem

Implanted pedicled autologous pericardium mimics vasculature tissue: Case report Naoki Masaki, MD, Osamu Adachi, MD, PhD, Shunsuke Kawamoto, MD, PhD,

A first start for lung transplantation?

Demonstration of persistent tumor cells 4 weeks after radiofrequency ablation of a pulmonary adenocarcinoma Stéphane Renaud, Marco Schiavon, MD, Nicola.

Impact of endothelial cell seeding on long-term patency and subendothelial proliferation in a small-caliber highly porous polytetrafluoroethylene graft

Joseph A. Dearani, MD, Michael J. Ackerman, MD, PhD

Decellularization reduces calcification while improving both durability and 1-year functional results of pulmonary homograft valves in juvenile sheep

Choice of second pericardial drainage tube for posterior placement

Tissue regeneration observed in a porous acellular bovine pericardium used to repair a myocardial defect in the right ventricle of a rat model Yen Chang,

Fenton H. McCarthy, MD, MS, Nimesh D. Desai, MD, PhD

Niv Ad, MD, Lawrence M. Wei, MD

Intrapulmonary psammomatous melanotic schwannoma

Instrumental variable methods in clinical research

Case reporter's notebook: The who, what, when, where, how, and why of extraction of a benign intracaval tumor Verdi J. DiSesa, MD, MBA The Journal of.

Marc Licker, MD, John Diaper, RA

Thrombosis following mitral and tricuspid valve-in-valve replacement

Passing the torch The Journal of Thoracic and Cardiovascular Surgery

Sutureless valve implantation: Every detail counts

Vascularity of human atrioventricular valves: A myth or fact?

Pheochromocytoma Presenting as Fever of Unknown Origin

Nonintubated thoracoscopic surgery for pulmonary lesions in both lungs

The origins of open heart surgery at the University of Minnesota 1951 to 1956 Richard A. DeWall, MD The Journal of Thoracic and Cardiovascular Surgery

The Journal of Thoracic and Cardiovascular Surgery

Discussion The Journal of Thoracic and Cardiovascular Surgery

The future of cardiac surgery training: A survival guide

Ventricular assistant in restrictive cardiomyopathy: Making the right connection Robert D.B. Jaquiss, MD The Journal of Thoracic and Cardiovascular Surgery

Giant tracheocele The Journal of Thoracic and Cardiovascular Surgery

Hope should not spring eternal

Quiz Page January 2010 American Journal of Kidney Diseases

“The more things change…”: The challenges ahead

Toward a more rational approach in treating type B aortic dissection

Ryan R. Davies, MD The Journal of Thoracic and Cardiovascular Surgery

Apples remain apples NO matter what

Did you like Terminator 3 better than Terminator 2

Lessons learned from Melody valve retrieved at transplantation

Descending thoracic and thoracoabdominal aortic aneurysms: “Busted”

Presentation transcript:

Mesothelium regeneration on acellular bovine pericardia loaded with an angiogenic agent (ginsenoside Rg1) successfully reduces postsurgical pericardial adhesions Yen Chang, MD, Po-Hong Lai, MS, Chung-Chi Wang, MD, Sung-Ching Chen, PhD, Wei-Chun Chang, MS, Hsing-Wen Sung, PhD The Journal of Thoracic and Cardiovascular Surgery Volume 132, Issue 4, Pages 867-874.e3 (October 2006) DOI: 10.1016/j.jtcvs.2006.06.029 Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Photographs of the e-PTFE, cellular, acellular, and acellular/Rg1 patches (marked by * at one of the corners of each implanted patch) retrieved at 3 months after surgery. Arrows point to the sites of pericardial adhesions. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 867-874.e3DOI: (10.1016/j.jtcvs.2006.06.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Photomicrographs (stained with hematoxylin and eosin; original magnification, 200×) of the e-PTFE, Cellular, Acellular, and Acellular/Rg1 patches retrieved at 3 months after surgery. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 867-874.e3DOI: (10.1016/j.jtcvs.2006.06.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Photomicrographs of the acellular and acellular/Rg1 patches retrieved at 3 months after surgery: immunohistochemical stains identified neocollagen type III (brown staining; original magnification, 800×); van Gieson stain identified mesothelial cells (original magnification, 800×). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 867-874.e3DOI: (10.1016/j.jtcvs.2006.06.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E1 Photomicrographs (stained with hematoxylin and eosin [H&E]; original magnification, 200×) and scanning electron micrographs (SEM) of the Cellular and Acellular patches used in the study. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 867-874.e3DOI: (10.1016/j.jtcvs.2006.06.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E2 Photomicrographs (stained with hematoxylin and eosin; original magnification, 200×) of the e-PTFE, Cellular, Acellular, and Acellular/Rg1 patches retrieved at 1 month after surgery. The Journal of Thoracic and Cardiovascular Surgery 2006 132, 867-874.e3DOI: (10.1016/j.jtcvs.2006.06.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure E3 Photomicrographs of the Acellular and Acellular/Rg1 patches retrieved at 3 months after surgery: stained with Factor VIII (original magnification, 800×), Masson trichrome (original magnification, 200×), a monoclonal antibody against α-smooth muscle actin (α-SMA; brown staining; original magnification, 800×), and safranin O (red staining; original magnification, 200×). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 867-874.e3DOI: (10.1016/j.jtcvs.2006.06.029) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions