Biochemistry

ATOMS the smallest unit of an element.

MOLECULE A molecule is formed when two or more atoms join together chemically. EX: O2 (oxygen gas)

COMPOUNDS A compound is a molecule that contains at least two different elements. All compounds are molecules but not all molecules are compounds. EX: Na+Cl- (Salt)

Chemical Reactions Energy is absorbed or released, supplying energy for the organism. When one or more substances is changed into a new substance by breaking and forming new bonds. Ex. 2 H2 + O2 2 H2O (Reactants) (Products)

Homeostasis The body must stay in balance Enzymes help maintain homeostasis EX: Temp, pH, water concentration

Acids, Bases and pH Acids: lose hydrogen H+ in water 0-6.99 Ex: Orange juice ,vinegar and lemons 0-6.99 Bases: loses oxygen and hydrogen in water OH- 7.01-14 Ex: Soap, egg whites and baking soda pH: Concentration of hydrogen in solution, scale of 0-14

MACROMOLECULES Monomer  simple building block Polymer  large complex molecule made of many monomers Polymers are made from monomers

4 main polymers found in living things Carbohydrates Starches, sugars, and cellulose Lipids Phospholipids Nucleic Acid DNA: Deoxyribonucleic Acid RNA: Ribonucleic Acid Proteins Amino Acids Enzymes

Carbohydrates Group of chemicals that includes sugars, starch and cellulose. Used for short term energy storage Simple sugars are the easiest substance for your body to breakdown. Stored as glycogen, in muscles if not used quickly

Carbohydrates 3 Types Monosaccharide (one sugar) Disaccharide (two sugars) Polysaccharide (many sugars) Ex: Plant starch or animal glycogen Consist of C, H, and O in a 1:2:1 ratio Example: Glucose (C 6 H 12 O 6)

Monosaccharides one monomer (“building block”) of sugar simplest carbohydrate Example: Glucose (C 6 H 12 O 6)

Disaccharides Two monosaccharides covalently bonded Examples: sucrose lactose fructose glucose glucose galactose

Polysaccharides Cellulose Starch Potato is a plant stored starch Straight or branched chains of many sugar monomers Starch Potato is a plant stored starch Glycogen Animals store glycogen, which is produced in the liver or muscle Cellulose Cellulose is a non-digestible carbohydrate, the most abundant molecules on earth. Ex: Pencils, paper, wood.

Lipids Fats, oils, waxes, phospholipids, and steroids. Used for long term energy storage Fats act as an insulator Waxes act as a water repellant Keep leaves from drying out Make ducks feathers waterproof

Fats Saturated fats No double bonds Found in animal products Solid at room temp Unsaturated fats Contain one or more double bonds Found in plant products Liquid at room temp

Phospholipids Lipid that forms membrane of the cell Helps control movement in and out of the cell

Steroids Made up of 4 carbon rings Lipids with no fatty acids Made up of 4 carbon rings EX: Cholesterol, testosterone, estrogen Steroid back bone

Large molecules that contain hereditary information Nucleic Acids Large molecules that contain hereditary information Examples: DNA, RNA Chemical Make-up Phosphate: PO4 Sugar: C5H10O5 Nitrogen base: C5H5N5

Proteins Large complex molecules composed of smaller units called Amino Acids (AA) Made from combinations of 20 different AA Different amino acid combinations produce different proteins. Enzymes are a form of protein that help control chemical reactions.

What are Enzymes? Substrate Active Site They are : Proteins that act as catalysts: (Speed up rate of reaction by making atoms move faster) Substrate Any Substance that the enzyme works on Active Site The place on the enzyme that the substrate fits into

Why Are Enzymes So Important? Why are we devoting one whole lecture topic to a protein molecule? Nearly all chemical reactions in biological cells need enzymes to make the reaction occur fast enough to support life. From the Virtual Cell Biology Classroom on ScienceProfOnline.com Image: Jumping rope, Meagan E. Klein

Enzymes Facts End in “ase” Each enzyme is VERY specific to its substrate. Lactase breaks down Lactose What breaks down glucose?_______ What breaks down Sucrose?_______ Enzymes break molecules apart and also build them together!!! Does not get used up Speeds up reaction by lowering activation energy; (Energy needed to make reaction happen)

How Do Enzymes Work Enzymes & substrates fit together like a Lock & Key 1) Enzymes attach to substrate (whatever it is working on) 2) Chemical bonds are formed or broken in the substrate 3) Products of substrate are released 4) Enzyme goes back and grabs another substrate, and continues this process until the substrate is all broken down

Enzymes can be destroyed by high temperatures The high temperatures change the shape of the enzyme, denaturing it Why high fevers can kill us Cooking veggies is bad because we lose good enzymes Other factors that effect enzymes: pH Substrate Concentration Enzyme Concentration