Erythropoietin Surprises: An Immune Saga

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Presentation transcript:

Erythropoietin Surprises: An Immune Saga Hal E. Broxmeyer Immunity Volume 34, Issue 1, Pages 6-7 (January 2011) DOI: 10.1016/j.immuni.2011.01.004 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Diagram of Targets and Possible Targets Responsive to Action(s) of Erythropoietin The originally described action of erythropoietin was on enhancing proliferation and survival of cells within the erythroid system, with one target for erythropoiesis (production of red blood cells) being the erythroid progenitor cell (defined functionally as a burst forming unit-erythroid [BFU-E]) (Shaheen and Broxmeyer, 2009). Recently, other targets of erythropoietin have been reported (Shaheen and Broxmeyer, 2009; Nairz et al., 2011). Immunity 2011 34, 6-7DOI: (10.1016/j.immuni.2011.01.004) Copyright © 2011 Elsevier Inc. Terms and Conditions