Unit 4 Part 3 Cellular Respiration: Mitochondria, Krebs & Oxidative Phosphorylation

Mitochondria Be able to identify: Inner membrane Outer membrane Cristae Matrix

Cellular Respiration Location?

Cellular respiration The process: Reactants (inputs): Glucose & Oxygen Products (Outputs): CO2, H2O & ATP

Electron Carriers in CR NAD+  NADH FAD+  FADH2

Stuff… Oxidation Reduction Means to LOSE an electron Means to GAIN an electron Two ways to remember: OIL RIG or LEO the lions says GER

Cellular Respiration Glycolysis/Bridging Process (substrate-level phosphorylation) Krebs Cycle/Citric Acid Cycle (substrate-level phosphorylation) Electron Transport Chain (oxidative phosphorylation)

Krebs Cycle aka Citric Acid Cycle Location--Matrix of mitochondria Aerobic  requires O2 as final e- acceptor Produces: CO2 (from carbonyl) NADH FADH2 ATP

Krebs….part 1 Pay attention to what we start with & what is being made!

Krebs….part 2 Pay attention to what is being made!

Krebs….part 3 Pay attention to what is being made!

Krebs….part 4 Pay attention to what is being made!

Electron Transport Chain Location--Membrane of cristae Aerobic  requires O2 (final electron acceptor) Follow the electrons—and protons! Animation vcell.ndsu.nodak.edu/animations/etc/first.htm

Oxidative Phosphorylation Electrons power proton pumps (which are imbedded proteins)  pump H+ into intermembrane space (ETC) Generates ATP when H+ diffuse back into matrix thru ATP Synthase (Chemiosmosis) NAD+ powers 3 pumps  3 ATP FAD+ powers 2 pumps  2 ATP http://www.nature.com/nrg/journal/v2/n5/animation/nrg0501_342a_swf_MEDIA1.html

Oxidative Phosphorylation e- transferred to oxygen through proton pumps  builds up proton gradient Generates ATP through ATP Synthase