Erika Lerch, MD, Ulrich R. Müller, MD

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Presentation transcript:

Long-term protection after stopping venom immunotherapy: Results of re-stings in 200 patients Erika Lerch, MD, Ulrich R. Müller, MD Journal of Allergy and Clinical Immunology Volume 101, Issue 5, Pages 606-612 (May 1998) DOI: 10.1016/S0091-6749(98)70167-8 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 1 Skin test EPCs (arithmetic mean values) to BV (above) and VV (below) in patients with relapse (BV, n = 19; VV, n = 6) and continued protection (BV, n = 38; VV, n = 12). Significant decrease during VIT (p < 0.01) is observed in protected patients and patients with relapse on VIT with BV and in protected patients on VIT with VV. No significant difference between patients with relapse and continued protection is found at any time. Journal of Allergy and Clinical Immunology 1998 101, 606-612DOI: (10.1016/S0091-6749(98)70167-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 2 Specific IgE (geometric mean values) to BV (above) and VV (below) in patients with relapse (BV, n = 19; VV, n = 6) and continued protection (BV, n = 38; VV, n = 12). Significant decrease of sIgE during VIT is observed for patients with relapse and continued protection on VIT with BV (p < 0.01). There is only an insignificant further decrease after stopping VIT. At no time is there any significant difference between patients with relapse and continued protection. Journal of Allergy and Clinical Immunology 1998 101, 606-612DOI: (10.1016/S0091-6749(98)70167-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig. 3 Specific IgG (geometric mean values) to BV (above) and to VV (below) in patients with relapse (BV, n = 19; VV, n = 6) and continued protection (BV, n = 38; VV, n = 12). Slight but insignificant increase of sIgG is observed in all groups during VIT and strong decrease after its termination, which reaches statistical significance (p < 0.03) in both groups after treatment with BV. At no time is there significant difference between patients with relapse and continued protection. Journal of Allergy and Clinical Immunology 1998 101, 606-612DOI: (10.1016/S0091-6749(98)70167-8) Copyright © 1998 Mosby, Inc. Terms and Conditions