Prolonged trauma-induced increase of inflammatory cytokines in synovial fluid after surgical reconstruction of anterior cruciate ligament ruptures compared.

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Prolonged trauma-induced increase of inflammatory cytokines in synovial fluid after surgical reconstruction of anterior cruciate ligament ruptures compared to rehabilitation alone: an exploratory analysis in the kanon trial  S. Larsson, R. Frobell, L.S. Lohmander, A. Struglics  Osteoarthritis and Cartilage  Volume 24, Pages S330-S331 (April 2016) DOI: 10.1016/j.joca.2016.01.591 Copyright © 2016 Terms and Conditions

Figure 1 Cytokine levels (pg/ml) in synovial fluid (sf) at six visits over five years after ACL injury organized as treated. Circles and error bars, mean log concentrations and 95% confidence intervalls (CI) of patients at each visit. Filled circles; higher levels with early and/or delayed reconstruction compared to Rehab alone at the same visit. Empty circles; no differences between all three groups, or no difference compared with Rehab alone at the same visit. Dashed line and dark grey area, mean and 95% CI of the knee-healthy reference group. Osteoarthritis and Cartilage 2016 24, S330-S331DOI: (10.1016/j.joca.2016.01.591) Copyright © 2016 Terms and Conditions

Figure 2 Half-life concentration of cytokines in synovial fluid (sf) in the as-treated groups. Osteoarthritis and Cartilage 2016 24, S330-S331DOI: (10.1016/j.joca.2016.01.591) Copyright © 2016 Terms and Conditions