LIFE: Reduction in primary end-point events seen with reduction of LVH by two electrocardiographic criteria End point % reduction with each 1050-mm x ms [1 SD] decrease in Cornell product Hazard ratio (95% CI) % reduction with each 10.5-mm [1 SD] decrease in Sokolow-Lyon voltage CV death, nonfatal MI, nonfatal stroke 14 0.86 (0.82-0.90)* 17 0.83 (0.78-0.88)* *p<0.001 Okin PM et al. JAMA 2004; 292: 2343-2349.
LIFE: Risk of composite end point with regression of LV mass index Hazard ratio (95% CI) per 1 SD (25.3) in LV mass index p CV death, MI or stroke 0.78 (0.65-0.94) 0.009 Devereux RB et al. JAMA 2004; 292:2350-2356.