Substance P: Pivotal roles in pain and pancreatitis

Slides:



Advertisements
Similar presentations
Somatic Sensation of the Face and Head
Advertisements

Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 35 Somatosensory Function, Pain, and Headache.
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Human Anatomy & Physiology, Sixth Edition Elaine N. Marieb PowerPoint ® Lecture.
The Nervous System Intro Qs: pg Structures of the nervous system: 1.List the structures that make up the nervous system. 2.What is a nerve? 3.What.
The Nervous System An Introduction. Standards . Students know how the complementary activity of major body systems provides cells with oxygen and nutrients.
By: Celeste Anderson. The Nervous System The nervous system is a compound group of nerves and special cells called neurons which send specific messages.
CONTROL OF MUSCLE MOVEMENT D. C. MIKULECKY DEPARTMENT OF PHYSIOLOGY.
THE NERVOUS SYSTEM BY Kayla Lowery. MAJOR FUNCTIONS! SOME OF THE MAIN FUNCTIONS OF THE CENTRAL NERVOUS SYSTEM AND THE PERIPHERAL SYSTEM ARE:  To control.
An Introduction. Standards  9a. Students know how the complementary activity of major body systems provides cells with oxygen and nutrients and removes.
The Nervous System Control and coordinate the body parts and processes. It receives sensory stimuli from internal and external environments. It responds.
05. The Trigeminal System Somatic Sensation of the Face and Head David A. Morton, Ph.D. Thursday February 7 th, 2013.
The Nervous System (Peripheral Nervous System).  Peripheral nervous System (PNS): all the parts of the nervous system except for the brain & spinal cord.
Spinal Cord and Peripheral Nerve Stimulation Techniques for Neuropathic Pain Oscar A. de Leon-Casasola, MD Journal of Pain and Symptom Management Volume.
Autonomic Nervous System Dr. Donald Allen. Role of Autonomic Nervous System Homeostasis Internal Organs Vasculature.
© UWCM/SONMS/Pain/MJohn
Tissue: The Living Fabric Part D
THE NERVOUS SYSTEM Science 10.
Risk of Pain Medication Misuse After Spinal Cord Injury: The Role of Substance Use, Personality, and Depression  Jillian M.R. Clark, Yue Cao, James S.
W5D3H3: Sensory Receptors
SOMATOSENSORY PHYSIOLOGY (PAIN AND TEMPERATURE)
The generation of specific responses to stretch, pain or visceral sensations. Majoros Myrtill.
Does frog toxin represent a giant leap for treatment of pain?
Nervous System.
Paul M. George, Gary K. Steinberg  Neuron 
The Nervous System Chapter 4 Section 1.
Inhibitor of MAP kinase activation blocks colon cancer growth
Volume 143, Issue 5, Pages (November 2012)
An introduction to the cells & structures of your nervous system.
Neurovascular Aspects of Skin Neurogenic Inflammation
A New “Spin” on Recovery after Spinal Cord Injury
Glycine at the Gate—from Model to Mechanism
Mechanisms of inflammatory pain
Cooling the Itch via TRPM8
The Nervous System.
Volume 12, Issue 5, Pages (November 2010)
Neurophysiological, Neuroimmunological, and Neuroendocrine Basis of Pruritus  Martin Steinhoff, John Bienenstock, Martin Schmelz, Marcus Maurer, Ed Wei,
If you lose your nerves, at least you will not get kidney fibrosis!
Hot news about chili peppers
TRPs in Our Senses Current Biology
Louis L. Nguyen, MD, MBA, MPH  Journal of Vascular Surgery 
This Month in Gastroenterology
Overview of the Nervous System
Mechanisms of neuropathic pain
Protecting the brain and spinal cord
Recapitulating Atopic Dermatitis in Three Dimensions: Cross Talk between Keratinocytes and Nerve Fibers  Carlo Pincelli, Martin Steinhoff  Journal of.
Volume 137, Issue 6, Pages (June 2009)
Joao M. Braz, Mohammed A. Nassar, John N. Wood, Allan I. Basbaum 
PERIPHERAL NERVE SYSTEM
Fiber innervation is reduced in both central and peripheral targets of DRG neurons in Nav-Tsc2 mice. Fiber innervation is reduced in both central and peripheral.
Editorial Board Orthopedic Clinics Volume 48, Issue 3, (July 2017)
Editorial Board Orthopedic Clinics Volume 47, Issue 3, (July 2016)
A TR(I)P to Pruritus Research: Role of TRPV3 in Inflammation and Itch
Current Challenges in Glia-Pain Biology
An Itch To Be Scratched Neuron
Reviewer Acknowledgment
Overview of the Nervous System
The Brain and Spinal Cord
The Nervous System.
LIFESPAN OF ONE FOCUSED ULTRASOUND MEDIATED BLOOD-BRAIN BARRIER TREATMENT IN A MOUSE MODEL OF ALZHEIMER'S DISEASE  Charissa Poon, Kullervo Hynynen  Alzheimer's.
Nervous elements influencing intestinal inflammation and rotavirus diarrhea may lead to new treatments  Dan Gordon  Gastroenterology  Volume 118, Issue.
Experimental behaviour testing: pain
Editorial II: Opioids and the neuroimmune axis
Douglas C. McVey, Steven R. Vigna  Gastroenterology 
Potential routes taken by VZV during its life cycle.
The Nervous System.
Francie Moehring, Priyabrata Halder, Rebecca P. Seal, Cheryl L. Stucky 
Nerve Control of Blood Vessel Patterning
A representation of the central spinal and peripheral changes that accompany neuropathy. A representation of the central spinal and peripheral changes.
Functional abdominal pain syndrome
Itching as a systemic disease
Presentation transcript:

Substance P: Pivotal roles in pain and pancreatitis Dan Gordon  Gastroenterology  Volume 115, Issue 1, (July 1998) DOI: 10.1016/S0016-5085(98)70354-3 Copyright © 1998 Terms and Conditions

Substance P neurons in the dorsal root ganglia (DRG) send peripheral projections to the gut wall, where they innervate blood vessels and other structures, and to the spinal cord, where they interact in laminae II and III with neurons that transmit pain sensations to the brain. The present knockout experiments indicate that the most important spinal receptors mediating pain and the most important vascular and pancreatic receptors mediating neurogenic inflammation and pancreatitis are neurokinin 1 (NK1) receptors. Gastroenterology 1998 115, DOI: (10.1016/S0016-5085(98)70354-3) Copyright © 1998 Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.