Treatment of hypogammaglobulinemia in adults: A scoring system to guide decisions on immunoglobulin replacement  Shradha Agarwal, MD, Charlotte Cunningham-Rundles,

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Treatment of hypogammaglobulinemia in adults: A scoring system to guide decisions on immunoglobulin replacement  Shradha Agarwal, MD, Charlotte Cunningham-Rundles, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 131, Issue 6, Pages 1699-1701.e3 (June 2013) DOI: 10.1016/j.jaci.2013.01.036 Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Laboratory and clinical history parameters according to the scoring system for indications for initiation of immunoglobulin therapy in patients with hypogammaglobulinemia. AIHA, Autoimmune hemolytic anemia; FVC, forced vital capacity; ITP, idiopathic thrombocytopenic purpura; TLC, total lung capacity. Journal of Allergy and Clinical Immunology 2013 131, 1699-1701.e3DOI: (10.1016/j.jaci.2013.01.036) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Scoring decision tree. Ig, Immunoglobulin; IV, intravenous; SC, subcutaneous. Journal of Allergy and Clinical Immunology 2013 131, 1699-1701.e3DOI: (10.1016/j.jaci.2013.01.036) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Median laboratory, clinical, and cumulative scores versus decision to start immunoglobulin (Ig) therapy. Journal of Allergy and Clinical Immunology 2013 131, 1699-1701.e3DOI: (10.1016/j.jaci.2013.01.036) Copyright © 2013 American Academy of Allergy, Asthma & Immunology Terms and Conditions