IgM Anti-Ganglioside Antibodies Induced by Melanoma Cell Vaccine Correlate with Survival of Melanoma Patients  Takenori Takahashi, Timothy D. Johnson, Yumiko Nishinaka, Donald L. Morton, Reiko F. Irie  Journal of Investigative Dermatology  Volume 112, Issue 2, Pages 205-209 (February 1999) DOI: 10.1046/j.1523-1747.1999.00493.x Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 IgM anti-ganglioside antibodies by ELISA in sera of melanoma patients at weeks 0 and 4. All sera were tested at 1:200 dilution. The statistical differences in these results are tabulated in Table 1 . Journal of Investigative Dermatology 1999 112, 205-209DOI: (10.1046/j.1523-1747.1999.00493.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 2 Percentage of patients whose sera displayed an OD value higher than the cut-off OD value. The cut-off OD value was determined by taking the upper 95% confidence value for the 1 y survival group. The cut-off values were 0.270 for anti-GD2, 0.393 for anti-GM2, 0.278 for anti-GM3, and 0.490 for anti-GD3. □, 5 y group; , 2–5 y group;▪, 1 y group. The p value from a test of the odds ratio compares the percentage of high responders in 5 y and 2–5 y groups with that in the 1 y group. Journal of Investigative Dermatology 1999 112, 205-209DOI: (10.1046/j.1523-1747.1999.00493.x) Copyright © 1999 The Society for Investigative Dermatology, Inc Terms and Conditions