Experimental absorbable stent permits airway remodeling

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Presentation transcript:

Experimental absorbable stent permits airway remodeling Kuo-Sheng Liu, MD, Yun-Hen Liu, MD, Yi-Jie Peng, MD, Shih-Jung Liu, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 141, Issue 2, Pages 463-468 (February 2011) DOI: 10.1016/j.jtcvs.2010.08.008 Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 A, Dimensions of the stent component. B, Fabrication process of the bioresorbable PCL stents. The Journal of Thoracic and Cardiovascular Surgery 2011 141, 463-468DOI: (10.1016/j.jtcvs.2010.08.008) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 A comparison of bioresorbable PCL stents and commercial silicon stents. The Journal of Thoracic and Cardiovascular Surgery 2011 141, 463-468DOI: (10.1016/j.jtcvs.2010.08.008) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 A, In vitro weight variation of PCL stents at different times. B, In vitro and in vivo deformation rates of PCL stents at different times. The Journal of Thoracic and Cardiovascular Surgery 2011 141, 463-468DOI: (10.1016/j.jtcvs.2010.08.008) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 4 A, Immediate postoperative bronchoscopic picture showed blood in the trachea lumen; B, 1 week after surgery; C, 2 weeks after surgery; D, 4 weeks after surgery; E, 8 weeks after surgery; and F, 12 weeks after surgery. The Journal of Thoracic and Cardiovascular Surgery 2011 141, 463-468DOI: (10.1016/j.jtcvs.2010.08.008) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 5 A, Distal stent migration due to forceful push by bronchoscope at 1 week after surgery. B, In-stent secretion accumulation at 12 weeks after surgery. The Journal of Thoracic and Cardiovascular Surgery 2011 141, 463-468DOI: (10.1016/j.jtcvs.2010.08.008) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions

Figure 6 A, At 10 weeks after surgery, histological examination showed marked leukocyte infiltration in the submucosa of stented area. B, Submucosa leukocyte infiltration at 28 weeks after surgery. The Journal of Thoracic and Cardiovascular Surgery 2011 141, 463-468DOI: (10.1016/j.jtcvs.2010.08.008) Copyright © 2011 The American Association for Thoracic Surgery Terms and Conditions