A Tale of Two Rashes The American Journal of Medicine

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Presentation transcript:

A Tale of Two Rashes The American Journal of Medicine Bradley W. Richmond, MD, Mary Beth Cole, MD, Aruna Dash, MD, Anne Eyler, MD, Chad S. Boomershine, MD, PhD The American Journal of Medicine Volume 124, Issue 5, Pages 414-417 (May 2011) DOI: 10.1016/j.amjmed.2011.01.003 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Histologic glomerular analysis performed 10 years prior to the current admission. (A) Jones silver staining showing global endocapillary proliferation and small cellular crescent (arrowhead) and widespread basement membrane splitting (arrow in insert). Original magnification: ×400 (inset, ×2000). (B) Immunofluorescence staining for C3 complement showing 2+ diffuse, global irregular, granular mesangial, and capillary loop staining. Original magnification: ×800. The American Journal of Medicine 2011 124, 414-417DOI: (10.1016/j.amjmed.2011.01.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 2 The patient presented with two types of rash. (A) Hypopigmented plaques with overlying scale and an erythematous, slightly raised border were present on the chest, back, and right upper extremity. Atrophic, scarred plaques were present on the face and ears. (B) Violaceous, palpable, nonblanching papules (diameter, 2–3 mm) were present on both lower extremities. The American Journal of Medicine 2011 124, 414-417DOI: (10.1016/j.amjmed.2011.01.003) Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 3 (A) Histologic analysis of a right-upper arm skin biopsy showing acanthosis and parakeratosis with scale crust formation (B) and focal vacuolar change along the basal layer of the epidermis. The American Journal of Medicine 2011 124, 414-417DOI: (10.1016/j.amjmed.2011.01.003) Copyright © 2011 Elsevier Inc. Terms and Conditions