Polycythemia vera following autologous transplantation for AML: insights on the kinetics of JAK2V617F clonal dominance by Elisabetta Antonioli, Paola Guglielmelli,

Slides:

Advertisements

Similar presentations

Hematology The Study of Blood Blood contains cells, proteins, and sugars Red blood cells transport oxygen- erythrocytes White blood cells are part of the.

Advertisements

Objectives 1. Methods used to measure the different hematological values, and compare it with the normal values. 2. The calculation of RBC indices, their.

Stem cell concepts renew cancer research by John E. Dick Blood Volume 112(13): December 15, 2008 ©2008 by American Society of Hematology.

Nonpermissive HLA-DPB1 disparity is a significant independent risk factor for mortality after unrelated hematopoietic stem cell transplantation by Roberto.

Durable remissions with autologous stem cell transplantation for high-risk HIV-associated lymphomas by Amrita Krishnan, Arturo Molina, John Zaia, David.

Interim Results from a Phase 2, Multicenter, Single-Arm Study to Evaluate the Safety and Efficacy of Deferasirox after Hematopoietic Stem Cell Transplantation.

Generating AML-Specific Peripheral Blood Autologous Cytotoxic T-Lymphocytes (CTLs)‏ by Rohtesh S. Mehta, Xiaohua Chen, Antony Jeyaraj, and Paul Szabolcs.

by Paul A. Carpenter, Meei-Li Huang, and George B. McDonald

Determination of acute lung injury after repeated platelet transfusions by Laurence Corash, Jin Sying Lin, Claire D. Sherman, and Joseph Eiden Blood Volume.

© The Author(s) Published by Science and Education Publishing.

Hematopoietic Stem Cell Transplantation for Multiple Sclerosis: Collaboration of the CIBMTR and EBMT to Facilitate International Clinical Studies Marcelo.

Comparable results of umbilical cord blood and HLA-matched sibling donor hematopoietic stem cell transplantation after reduced-intensity preparative regimen.

The superiority of haploidentical related stem cell transplantation over chemotherapy alone as postremission treatment for patients with intermediate-

MBL: mostly benign lymphocytes, but…

Changes in Serologic Markers of Hepatitis B Following Autologous Hematopoietic Stem Cell Transplantation Ji Eun Uhm, Kihyun Kim, Tae Kyu Lim, Byeong-Bae.

by Muhammed A. Mir, Mrinal M. Patnaik, and Joerg Herrmann

Gupta V, Tallman MS, Weisdorf DJ

Prognostic factors for thrombosis and survival in PV, revisited

A Clinical Evaluation of the International Lymphoma Study Group Classification of Non-Hodgkin's Lymphoma Blood Volume 89(11): June 1, 1997 ©1997.

Successful Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplant in an Acute Leukemia Patient With Chemotherapy-Induced Marrow Aplasia and Progressive.

Female donors contribute to a selective graft-versus-leukemia effect in male recipients of HLA-matched, related hematopoietic stem cell transplants by.

The Hematopoietic Stem Cell Transplant Comorbidity Index (HCT-CI) Can Predict for Readmission Following Autologous Stem Cell Transplant for Lymphoma and.

by Thomas Rasmussen, Linda Jensen, Lone Honoré, and Hans Erik Johnsen

Superior Survival after Autologous vs

Clinical response to F16-IL2 and LDAC in patients with AML bone marrow involvement. Clinical response to F16-IL2 and LDAC in patients with AML bone marrow.

The Effect of Statin Use at the Time of Autologous Transplant on Response and Survival in Multiple Myeloma Mehdi Hamadani, Erinn Hade, Don M. Benson,

by Satish Gopal, William A. Wood, Stephanie J. Lee, Thomas C

Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma.

Functional neutrophils from human ES cells

Full hematopoietic engraftment after allogeneic bone marrow transplantation without cytoreduction in a child with severe combined immunodeficiency by Ronald.

JAK2V617F mutation and hydroxyurea treatment as determinants of immature platelet parameters in essential thrombocythemia and polycythemia vera patients.

by Jayesh Mehta Blood Volume 112(2): July 15, 2008

by Paul A. Carpenter, Meei-Li Huang, and George B. McDonald

Fludarabine-Based Nonmyeloablative Stem Cell Transplantation for Sickle Cell Disease with and without Renal Failure: Clinical Outcome and Pharmacokinetics

Christopher C. Dvorak, Rajni Agarwal, Gary V. Dahl, John J

A Population-Based Cohort Study of Late Mortality in Adult Autologous Hematopoietic Stem Cell Transplant Recipients in Australia Lesley J. Ashton, Renate.

New Light Chain Amyloid Response Criteria Help Risk Stratification of Patients by Day 100 after Autologous Hematopoietic Cell Transplantation Anita D'Souza,

Lymphocyte Subset Recovery and Outcome after Autologous Hematopoietic Stem Cell Transplantation for Plasma Cell Myeloma Jessica Rueff, Michael Medinger,

Emerging Importance of Mutational Analysis in Myelodysplastic Syndrome and Acute Myelogenous Leukemia Aaron T. Gerds, Matthew J. Walter, Bart L. Scott

by Geling Li, Emily Waite, and Julie Wolfson

Clonal heterogeneity as a driver of disease variability in the evolution of myeloproliferative neoplasms Janine Prick, Gerald de Haan, Anthony R. Green,

Disparity in Survival Outcome after Hematopoietic Stem Cell Transplantation for Hematologic Malignancies According to Area of Primary Residence Keshav.

Shigeo Fuji, Hermann Einsele, Bipin N. Savani, Markus Kapp

Hematopoietic Stem Cell Transplantation for Multiple Sclerosis: Collaboration of the CIBMTR and EBMT to Facilitate International Clinical Studies Marcelo.

What is quality in a transplant program?

by Ayalew Tefferi, Terra L. Lasho, Paola Guglielmelli, Christy M

Allogeneic Hematopoietic Stem Cell Transplantation in FLT3-ITD–Positive Acute Myelogenous Leukemia: The Role for FLT3 Tyrosine Kinase Inhibitors Post-

Haploidentical Hematopoietic Stem Cell Transplantation without In Vitro T Cell Depletion for Treatment of Hematologic Malignancies in Children Xiaojun.

Volume 2(Supplement 1):46-49

Low Serum Levels of Total Rabbit-IgG Is Associated with Acute Graft-Versus-Host Disease after Unrelated Donor Hematopoietic Stem Cell Transplantation:

Figure 2 Evolution of blood cell counts during interleukin (IL)–7 therapy Evolution of blood cell counts during interleukin (IL)–7 therapy The leukocyte.

Extramedullary Relapse of Acute Myelogenous Leukemia after Allogeneic Hematopoietic Stem Cell Transplantation: Better Prognosis Than Systemic Relapse

Bridge to transplant following Bv+Bs regimen.

Praveena Narayanan, Alexandra Wolanskyj, Shawna L. Ehlers, Mark R

Sequential allogeneic and autologous CAR-T–cell therapy to treat an immune-compromised leukemic patient by Jian-Ping Zhang, Rui Zhang, Shih-Ting Tsao,

Treatment versus Transplant for Challenging Hematologic Disorders

Erratum in Ledru et al. Alteration of tumor necrosis factor–α T-cell homeostasis following potent antiretroviral therapy: contribution to the development.

William Berquist, MD Gastrointestinal Endoscopy

Central nervous system–restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation by Hojun Li, Leslie A. Benson,

TP53 Mutations in AML Predict Adverse Outcome in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplant by Bartlomiej M Getta, Arnab Ghosh,

Fig. 4 PD-L1 expression is found in the spleen and the BM of mice transplanted with JAK2V617F-transduced bone marrow. PD-L1 expression is found in the.

Time-dependent survival estimation in post–polycythemia vera myelofibrosis. Time-dependent survival estimation in post–polycythemia vera myelofibrosis.

Mesenchymal Stem Cell-Derived Vesicles Reverse Hematopoietic Radiation Damage by Sicheng Wen, Laura R Goldberg, Mark S Dooner, John L Reagan, and Peter.

by Lucy A. Godley, and Akiko Shimamura

Patient Tregs express normal levels of suppression.

by Jan J. Cornelissen, and Didier Blaise

Maintenance Therapy with Low-Dose Azacitidine (AZA) after Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) for Relapsed or Refractory AML or MDS:

Stem cell transplant in MF: it’s time to personalize

Schedule-dependent impact of costimulated activated T-cell transfer on T-cell reconstitution after tandem stem cell transplant. Schedule-dependent impact.

Presentation transcript:

Polycythemia vera following autologous transplantation for AML: insights on the kinetics of JAK2V617F clonal dominance by Elisabetta Antonioli, Paola Guglielmelli, Giada Poli, Valeria Santini, Alberto Bosi, and Alessandro M. Vannucchi Blood Volume 110(13):4620-4621 December 15, 2007 ©2007 by American Society of Hematology

The progressive changes of hematologic parameters (hemoglobin [Hb], white blood cell count [WBC], and platelet count [PLT]; on the left y-axis) and of JAK2V617F allele burden (percent value; on the right y-axis) in samples collected at different times after... The progressive changes of hematologic parameters (hemoglobin [Hb], white blood cell count [WBC], and platelet count [PLT]; on the left y-axis) and of JAK2V617F allele burden (percent value; on the right y-axis) in samples collected at different times after AML diagnosis. Clinically relevant events (diagnosis of AML or PV, autologous hematopoietic stem-cell transplantation [HSCT], and onset of pruritus) are marked by arrows on the top of the figure. Elisabetta Antonioli et al. Blood 2007;110:4620-4621 ©2007 by American Society of Hematology