A Novel Classification of MUC1 Expression Is Correlated with Tumor Differentiation and Postoperative Prognosis in Non–Small Cell Lung Cancer Shinjiro.

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Presentation transcript:

A Novel Classification of MUC1 Expression Is Correlated with Tumor Differentiation and Postoperative Prognosis in Non–Small Cell Lung Cancer Shinjiro Nagai, MD, Kazumasa Takenaka, MD, Makoto Sonobe, MD, Eiji Ogawa, MD, Hiromi Wada, PhD, MD, Fumihiro Tanaka, PhD, MD Journal of Thoracic Oncology Volume 1, Issue 1, Pages 46-51 (January 2006) DOI: 10.1016/S1556-0864(15)31512-4 Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 MUCI expression in NSCLC with immunohistochemical staining. (A) High-grade polarized expression (HP) pattern of MUC1 expression in a well-differentiated papillary adenocarcinoma case (original magnification, ×100). (B) Depolarized (D) expression pattern of MUC1 in a poorly differentiated adenocarcinoma case (original magnification, ×200). Journal of Thoracic Oncology 2006 1, 46-51DOI: (10.1016/S1556-0864(15)31512-4) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Postoperative survival of NSCLC patients according to MUC1 expression pattern. HP, high-grade polarized expression; LP, low-grade polarized expression; D, depolarized expression. Journal of Thoracic Oncology 2006 1, 46-51DOI: (10.1016/S1556-0864(15)31512-4) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 3 Postoperative survival of lung adenocarcinoma patients according to MUC1 expression pattern. HP, high-grade polarized expression; LP, low-grade polarized expression; D, depolarized expression. Journal of Thoracic Oncology 2006 1, 46-51DOI: (10.1016/S1556-0864(15)31512-4) Copyright © 2006 International Association for the Study of Lung Cancer Terms and Conditions