Gen Expression Constitutive Enzymes not Regulated

Slides:



Advertisements
Similar presentations
Metabolic Regulation . : - Enzyme activity - Cell surface receptors.
Advertisements

Ch 18 Gene Regulation. Consider: A multicellular organism (Pliny) Do each of his cells have the same genes? Yes, with an exception: germ cells are haploid.
Genetic Regulatory Mechanisms. Control of Gene Expression Transcriptional control Clustering of genes with related function Coordinate control of genes.
Comparison of Genetic Material and Replication for Eukaryotes and Prokaryotes BacteriaArchaeaEukaryotes Genomehaploid; circular diploid; linear HistonesAbsentPresent;
Regulation and Control of Metabolism in Bacteria
Metabolic regulation Metabolic regulation: -Genetic level -Cellular level: - enzyme activity - Cell surface receptors.
1 SIGNAL TRANSDUCTION BACTERIA SENSE CHANGE IN ENVIRONMENT AND RESPOND TO IT TWO COMPONENT SIGNAL TRANSDUCTION SYSTEM PHOSPHO-RELAY SYSTEM SENSOR KINASE.
Enzyme Regulation. Constitutive enzymes –Enzymes needed at the same level all of the time Regulated enzymes –Enzymes needed under some conditions but.
Chapter 11 Molecular Mechanisms of Gene regulation Jones and Bartlett Publishers © 2005.
Regulating Gene Expression Microbes respond to changing environment – Alter growth rate – Alter proteins produced Must sense their environment – Receptors.
DNA, AND IN SOME CASES RNA, IS THE PRIMARY SOURCE OF HERITABLE INFORMATION Noneukaryotic Genetic Information.
Chapter 18 Regulation of Gene Expression.
CHAPTER 8 Metabolic Respiration Overview of Regulation Most genes encode proteins, and most proteins are enzymes. The expression of such a gene can be.
Operons. Structural gene Operon Polycistronic mRNA Operator Regulator gene Repressor Overview animation Overview animation.
Control of Prokaryotic Gene Expression. Prokaryotic Regulation of Genes Regulating Biochemical Pathway for Tryptophan Synthesis. 1.Produce something that.
AP Biology Chapter 18: Gene Regulation. Regulation of Gene Expression Important for cellular control and differentiation. Understanding “expression” is.
Regulation of transcription in prokaryotes
Operons. Big picture Prokaryotic control of genome expression Prokaryotic control of genome expression 2 levels of control 2 levels of control  Change.
Sites of regulation. Feedback inhibition Mechanism of allosteric inhibition.
1 Genetic regulation Genotype is not phenotype: bacteria possess many genes that they are not using at any particular time. Transcription and translation.
Regulation of Gene Expression. Prokaryotes –Constituitive Gene Expression (promoters) –Regulating Metabolism (promoters and operators) –Regulating Development.
Chapter 16 Control of Gene Expression. Topics to discuss DNA binding proteins Prokaryotic gene regulation Eukaryotic gene regulation.
Regulation of gene and cellular activity
Gene Regulation 8/24/2015. DNA Binding Proteins Histones Sequence specific DNA major grove Homodimeric Inverted repeats 8/24/2015.
Promoter sequences from 10 bacteriophage and bacterial genes
Announcements Exam 3: All material covered since exam 2 including:
Differential Expression of Genes  Prokaryotes and eukaryotes precisely regulate gene expression in response to environmental conditions  In multicellular.
Genetics: Chapter 7. What is genetics? The science of heredity; includes the study of genes, how they carry information, how they are replicated, how.
Chapter 16 Outline 16.4 Some Operons Regulate Transcription Through Attenuation, the Premature Termination of Transcription, Antisense RNA Molecules.
Regulation of gene expression in prokaryotes Katalin Kiss Dept. of Medical Biology
Transposon “Jumping Genes” Insertion Sequence
Regulation of Gene expression by E. Börje Lindström This learning object has been funded by the European Commissions FP6 BioMinE project.
1 Gene regulation in Prokaryotes Bacteria were models for working out the basic mechanisms, but eukaryotes are different. Some genes are constitutive,
Trp Operon A brief description. Introduction a repressible system In this system, though, unlike the lac operon, the gene for the repressor is not adjacent.
Gene Regulation, Part 1 Lecture 15 Fall Metabolic Control in Bacteria Regulate enzymes already present –Feedback Inhibition –Fast response Control.
Regulation of Gene Expression in Prokaryotes
Regulation of Gene Expression in Prokaryotes
Prokaryotes vs Eukaryotes
Gene Regulation Packet #46 Chapter #19.
Regulation of Gene Expression in Bacteria and Their Viruses
Regulation of Gene Expression Chromosomal Map begins at OriC; units of minutes. –Only structural genes for enzymes are shown here. –Their control regions.
José A. Cardé Serrano, PhD Universidad Adventista de las Antillas Biol 223 Genética Agosto 2010.
Gene Expression Chapter 16. DNA regulatory sequence All on DNA Promoters – Start transcription Promoters – Start transcription Terminators – End Transcription.
Warm Up Write down 5 times it would be beneficial for a gene to be ‘turned off’ and the protein not be expressed 1.
Chapter 8, part B Microbial Genetics.
Regulation of Gene Expression
The Operon.
Gene Regulation in Bacteria
Control of Gene Expression
Figure 18.3 trp operon Promoter Promoter Genes of operon DNA trpR trpE
Differential Expression of Genes
Goals today: Describe the parts of an operon
Regulation of gene and cellular activity
Control of Gene Expression
Gene Regulation in Prokaryotes
Daily Warm-Up Tuesday, Jan. 7th
Ch 18: Regulation of Gene Expression
Agenda 3/16 Genes Expression Warm Up Prokaryotic Control Lecture
Regulation of Gene Expression
Introduction to Gene Expression
Regulation of Gene Expression
Gene Regulation Packet #22.
Review Warm-Up What is the Central Dogma?
Review Warm-Up What is the Central Dogma?
The Chapter 15 Homework is due Wednesday, January 30 at 11:59 pm.
Chapter 18 Bacterial Regulation of Gene Expression
Review Warm-Up What is the Central Dogma?
Objective 3: TSWBAT recognize the processes by which bacteria respond to environmental changes by regulating transcription.
Control of Prokaryotic (Bacterial) Genes
Regulation of Gene Transcription
Presentation transcript:

Gen Expression Constitutive Enzymes not Regulated Most Enzymes Can Have Their Activity Regulated Feedback Inhibition

Allosteric Sites

Isozymes Covalent Modification

Regulation of Transcription Enzyme Repression Repressor Corepressor Operator Operon

Induction Inducer

Control Negative Control Positive Control Activator Protein Regulon DNA Binding Proteins Histones

Attenuation

Attenuator Leader Sequence

Catabolite Repression Global control Diauxic growth Catabolite Repressor Protein cAMP

Other Global Controls Quorum Sensing Alternative Sigma Factors Proteases Chaperonin

Two Component Regulation Signal Transduction Sensor Kinase Response Regulator

Others Chemotaxis Antisense RNA Triple DNA

Regulation of Gene Expression Constitutive Isozymes Corepressor Enzymes Covalent Operator Regulation of Modification Operon Enzyme Repression Activity Transcription Repressor Feedback Protein Inhibition Induction Negative Control Allosteric Site Inducer

Gene Expression 2 Negative DNA Binding Catabolite Control Proteins Repression Positive Attenuation Leader Activator Sequence Protein Attenuator cAMP Regulon Global Control Quorum Histones Diauxic Growth Sensing

Gene Expression 3 Other Global Signal Antisense Controls Transduction mRNA Alternative 2-Component Triple DNA Sigma Factors Regulation Proteases Sensor Kinases Chaperonin Response Regulator Chemotaxis