Three-parent in vitro fertilization: gene replacement for the prevention of inherited mitochondrial diseases  Paula Amato, M.D., Masahito Tachibana, M.D.,

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Three-parent in vitro fertilization: gene replacement for the prevention of inherited mitochondrial diseases  Paula Amato, M.D., Masahito Tachibana, M.D., Ph.D., Michelle Sparman, M.S., Shoukhrat Mitalipov, Ph.D.  Fertility and Sterility  Volume 101, Issue 1, Pages 31-35 (January 2014) DOI: 10.1016/j.fertnstert.2013.11.030 Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Pronuclear transfer technique. Reproduced from Bredenoord and Braude (18), with permission from BMJ Publishing Group Ltd. Fertility and Sterility 2014 101, 31-35DOI: (10.1016/j.fertnstert.2013.11.030) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Spindle transfer technique. Image reproduced from www.hfea.gov.uk/6372.html, with permission. Fertility and Sterility 2014 101, 31-35DOI: (10.1016/j.fertnstert.2013.11.030) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions

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