J. K. Sarin, H. Brommer, D. Argüelles, P. H. Puhakka, S. I. Inkinen, I

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Multimodality scoring of chondral injuries in the equine fetlock joint ex vivo J.K. Sarin, H. Brommer, D. Argüelles, P.H. Puhakka, S.I. Inkinen, I.O. Afara, S. Saarakkala, J. Töyräs Osteoarthritis and Cartilage Volume 25, Issue 5, Pages 790-798 (May 2017) DOI: 10.1016/j.joca.2016.12.007 Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Study design. The arthroscopic ICRS scoring was performed by two experienced equine surgeons two times, and the histological scoring by three evaluators three times. Osteoarthritis and Cartilage 2017 25, 790-798DOI: (10.1016/j.joca.2016.12.007) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 The alignment (A) and output signal (D) of the hand-held indentation device for probing the mechanical properties of articular cartilage are shown. Higher resolution of OCT enables enhanced visualization of cartilage surface (B vs E), whereas US enables superior detection of subchondral bone (C vs F). Same lesions are indicated with arrows. Osteoarthritis and Cartilage 2017 25, 790-798DOI: (10.1016/j.joca.2016.12.007) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Biomechanical response of equine cartilage as a function of ICRS score. (A) An expected decrease of cartilage stiffness (ELab) is observed with higher ICRS score (histology). (B) Notable difference in cartilage stiffness (ELab) is observed between ICRS grades 0 and 1 based on the average score of multimodal scorings. (C–D) A similar trend is not apparent with Artscan measurements (EArtscan) and ICRS scores (histology) or the average score of multimodal scorings. A single measurement point is not visible (27.7 MPa, at ICRS 1 and ICRS 0) in subfigures C and D, respectively. Osteoarthritis and Cartilage 2017 25, 790-798DOI: (10.1016/j.joca.2016.12.007) Copyright © 2016 Osteoarthritis Research Society International Terms and Conditions