Effect of prolonged treatment with compression stockings to prevent post-thrombotic sequelae: A randomized controlled trial Markus Aschwanden, MD, Christina.

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Presentation transcript:

Effect of prolonged treatment with compression stockings to prevent post-thrombotic sequelae: A randomized controlled trial Markus Aschwanden, MD, Christina Jeanneret, MD, Michael T. Koller, MD, MSc, Christoph Thalhammer, MD, Heiner C. Bucher, MD, MPH, Kurt A. Jaeger, MD Journal of Vascular Surgery Volume 47, Issue 5, Pages 1015-1021 (May 2008) DOI: 10.1016/j.jvs.2008.01.008 Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 1 Trial profile. CVI, Chronic venous insufficiency C4 to C6 (CEAP classification)10; DVT, proximal deep vein thrombosis. *Other reasons included frailty, dementia, and living too remote from the study center. Journal of Vascular Surgery 2008 47, 1015-1021DOI: (10.1016/j.jvs.2008.01.008) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 2 Kaplan-Meier estimates of survival without post-thrombotic skin changes in the intervention (dotted line) and control groups (dashed line). A, Survival free of post-thrombotic skin changes for the whole study population. B, Treatment effects specific to men. C, Treatment effects specific to women. Journal of Vascular Surgery 2008 47, 1015-1021DOI: (10.1016/j.jvs.2008.01.008) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 3 Subgroup-analysis of primary end point. CI, Confidence interval; DVT, ipsilateral deep vein thrombosis; HR, hazard ratio. Journal of Vascular Surgery 2008 47, 1015-1021DOI: (10.1016/j.jvs.2008.01.008) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions

Fig 4 Probability of presence of symptoms over time in controls (circles) and intervention group (crosses). Symptom presence means at least one of five symptoms present at any follow-up examination. Error bars indicate 95% confidence interval per treatment arm. Journal of Vascular Surgery 2008 47, 1015-1021DOI: (10.1016/j.jvs.2008.01.008) Copyright © 2008 The Society for Vascular Surgery Terms and Conditions