Improving CABG Surgery

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Presentation transcript:

Improving CABG Surgery Amir Durrani Ben Hoagland Santosh Tumkur Lucas Burton Advisor: Thomas P. Ryan, Ph.D.

Project Goals Improve harvested vessel attachment Design device to aid in grafting Reduce suturing difficulty Improve local stabilization

Overview of Off-Pump CABG Coronary Artery Bypass Graft Procedure to introduce increased blood flow to occluded coronary arteries Harvested vessels grafted to coronary arteries

Market Potential 150,000 Off-pump CABG surgeries performed worldwide each year Charge for a CABG procedure ranges from $37,000 and $72,000 per case $26 Billion spent per year on CABG surgeries Use of beating heart techniques has grown more than 40% each year since 1997

Problems Stabilization is required to perform CABG on a beating heart Effective vessel-artery contact is imperative Complex suturing techniques required Current stabilizers don’t provide adequate local stabilization of graft site Heart positioning problems Heart hemodynamics

Possible Solution 1 Y-joint grafting device Shunt-like External harvested vessel attachment Intra-vascular component Absorbable Biocompatible Beveled attachment point

Possible Solution 2 “Umbrella” grafting device Circular surface is inserted into coronary artery and adheres to inner vessel surface Provides a stable vessel connection to facilitate suturing

Progress Made Redirected project toward efficient suturing techniques with improved stabilization Obtained feedback from biomaterials experts Utilized Innovation Workbench Built crude models

Current Status Using Ratner as biomaterial reference Seeking feedback from Dr.’s Greelish and Merrill regarding models Acquired access to Dr. Jansen’s lab and storage facility Narrowing solution options

Future Plans Develop prototypes Continue researching possible solutions Continue consultation with surgeons and engineers for feedback Test scaled down prototypes on dog and pig hearts Alter design based on feedback and prototype test results