M.R.J. Sury, A. Worley, S.G. Boyd  British Journal of Anaesthesia 

Slides:



Advertisements
Similar presentations
Implantable cardioverter-defibrillator
Advertisements

The Effects of Levodopa and Deep Brain Stimulation on Subthalamic Local Field Low-Frequency Oscillations in Parkinson's Disease Neurosignals 2013;21:89-98.
Concentration-dependent suppression of F-waves by sevoflurane does not predict immobility to painful stimuli in humans†  J.H. Baars, D. Kalisch, K.F.
Subclinical rhythmic EEG discharge of adults: “SREDA in a child”
Ketamine increases the frequency of electroencephalographic bicoherence peak on the α spindle area induced with propofol  K. Hayashi, N. Tsuda, T. Sawa,
G.B. Drummond, A. Bates, J. Mann, D.K. Arvind 
A national survey of anaesthetists (NAP5 Baseline) to estimate an annual incidence of accidental awareness during general anaesthesia in the UK†  J.J.
Predictive performance of eleven pharmacokinetic models for propofol infusion in children for long-duration anaesthesia  M Hara, K Masui, D.J. Eleveld,
Sevoflurane therapy for life-threatening asthma in children
Functional walking capacity as an outcome measure of laparoscopic prostatectomy: the effect of lidocaine infusion  S. Lauwick, D.J. Kim, G. Mistraletti,
Pharmacokinetic parameter sets of alfentanil revisited: optimal parameters for use in target controlled infusion and anaesthesia display systems  N Sigmond,
Effect of adductor canal block on pain in patients with severe pain after total knee arthroplasty: a randomized study with individual patient analysis 
Proof of concept evaluation of the electroencephalophone as a discriminator between wakefulness and general anaesthesia  J Glen, B Porr, R Hamilton, L.
E. Olofsen, J.W. Sleigh, A. Dahan  British Journal of Anaesthesia 
Howell S.J. , Sear J.W. , Foëx P   British Journal of Anaesthesia 
Explaining Entropy responses after a noxious stimulus, with or without neuromuscular blocking agents, by means of the raw electroencephalographic and.
Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine,
Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram 
Volume 49, Issue 3, Pages (February 2006)
O. Akeju, K. J. Pavone, J. A. Thum, P. G. Firth, M. B. Westover, M
Electroencephalographic markers of brain development during sevoflurane anaesthesia in children up to 3 years old  L. Cornelissen, S.E. Kim, J.M. Lee,
Comparison of pattern of breathing with other measures of induction of anaesthesia, using propofol, methohexital, and sevoflurane†  T.L. Strickland, G.B.
B. Saugel, M. Cecconi, J.Y. Wagner, D.A. Reuter 
Behaviour of spectral entropy, spectral edge frequency 90%, and alpha and beta power parameters during low-dose propofol infusion  P. Mahon, B.R. Greene,
Inflating LMA with normal saline: 14 yr after
Attenuation of high-frequency (30–200 Hz) thalamocortical EEG rhythms as correlate of anaesthetic action: evidence from dexmedetomidine  G. Plourde, F.
Fluoride excretion in children after sevoflurane anaesthesia
T Emerick, D Metro, R Patel, T Sakai  British Journal of Anaesthesia 
Validation of the index of consciousness during sevoflurane and remifentanil anaesthesia: a comparison with the bispectral index and the cerebral state.
Sugammadex administration results in arousal from intravenous anaesthesia: a clinical and electroencephalographic observation  T. Chazot, G. Dumont, M.
Population pharmacokinetics of nalbuphine after surgery in children
Comparison of changes in electroencephalographic measures during induction of general anaesthesia: influence of the gamma frequency band and electromyogram.
Awareness and the EEG power spectrum: analysis of frequencies
Development of acute tolerance to the EEG effect of propofol in rats†
EEG-controlled closed-loop dosing of propofol in rats
B. Allaouchiche, F. Duflo, J.-P. Tournadre, R. Debon, D. Chassard 
Faster wash-out and recovery for desflurane vs sevoflurane in morbidly obese patients when no premedication is used  L. La Colla, A. Albertin, G. La Colla,
Comparison of motor-evoked potentials monitoring in response to transcranial electrical stimulation in subjects undergoing neurosurgery with partial vs.
Comparison of Bispectral Index and Entropy values with electroencephalogram during surgical anaesthesia with sevoflurane†  A.J. Aho, K. Kamata, V. Jäntti,
H. J. Kim, H. -C. Lee, Y. S. Jung, J. Lee, J. J. Min, D. -M. Hong, E
Pharmacodynamic changes with vecuronium in sepsis are associated with expression of α7- and γ-nicotinic acetylcholine receptor in an experimental rat.
Population pharmacokinetics of ε-aminocaproic acid in adolescents undergoing posterior spinal fusion surgery  P.A. Stricker, M.R. Gastonguay, D. Singh,
Comparative study of topical anaesthesia with lidocaine 2% vs levobupivacaine 0.75% in cataract surgery  S.A. Fernández, E. Dios, J.C. Diz  British Journal.
Comparison of 1% and 2% lidocaine epidural anaesthesia combined with sevoflurane general anaesthesia utilizing a constant bispectral index  A Shono, S.
Do old pharmacokinetic parameter estimates predict new data?
Local Origin of Field Potentials in Visual Cortex
Relationship between approximate entropy and visual inspection of irregularity in the EEG signal, a comparison with spectral entropy  A. Anier, T. Lipping,
M. A. Levin, G. W. Fischer, H. -M. Lin, P. J. McCormick, M. Krol, D. L
Hyperventilation-induced hypocapnia changes the pattern of electroencephalographic bicoherence growth during sevoflurane anaesthesia  K. Hayashi, M. Fujikawa,
The Ageing Brain: Age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia  P.L. Purdon, K.J. Pavone, O.
Falls and major orthopaedic surgery with peripheral nerve blockade: a systematic review and meta-analysis  R.L. Johnson, S.L. Kopp, J.R. Hebl, P.J. Erwin,
Validation of a measurement tool for self-assessment of teamwork in intensive care  J Weller, B Shulruf, J Torrie, R Frengley, M Boyd, A Paul, B Yee, P.
Effects of different remifentanil target concentrations on MAC BAR of sevoflurane in gynaecological patients with CO2 pneumoperitoneum stimulus  Z.-Y.
Bibliometrics of anaesthesia researchers in the UK
Implantable cardioverter-defibrillator
Impact of age on both BIS values and EEG bispectrum during anaesthesia with sevoflurane in children  E Wodey, O Tirel, J.Y. Bansard, A Terrier, C Chanavaz,
J Lee, S Gupta, C Price, A.P. Baranowski 
Validity of the 6 min walk test in prediction of the anaerobic threshold before major non- cardiac surgery  R.C.F. Sinclair, A.M. Batterham, S. Davies,
Chronic widespread pain, including fibromyalgia: a pathway for care developed by the British Pain Society  J. Lee, B. Ellis, C. Price, A.P. Baranowski 
T. Kerforne, M. Chaillan, L. Geraud, O. Mimoz 
Sufentanil administration guided by surgical pleth index vs standard practice during sevoflurane anaesthesia: a randomized controlled pilot study†  M.
Voltage changes in the lithium dilution cardiac output sensor after exposure to blood from horses given xylazine  T.D. Ambrisko, Y. Moens  British Journal.
Median effective dose (ED50) of paracetamol and morphine for postoperative pain: a study of interaction  A. Zeidan, J.X. Mazoit, M. Ali Abdullah, H. Maaliki,
H.D. Aya, M. Cecconi, M. Hamilton, A. Rhodes 
Study to determine the repeatability of supra-sternal Doppler (ultrasound cardiac output monitor) during general anaesthesia: effects of scan quality,
Monitoring level of sedation with bispectral EEG analysis: comparison between hypothermic and normothermic cardiopulmonary bypass†  D. Schmidlin, P. Hager,
R.L. Johnson, E.K. Cannon, C.B. Mantilla, D.A. Cook 
Anaesthetic drugs and survival: a Bayesian network meta-analysis of randomized trials in cardiac surgery  G. Landoni, T. Greco, G. Biondi-Zoccai, C. Nigro.
Performance of entropy and Bispectral Index as measures of anaesthesia effect in children of different ages†  A.J. Davidson, G.H. Huang, C.S. Rebmann,
George D. Dickinson, Ian Parker  Biophysical Journal 
Presentation transcript:

Age-related changes in EEG power spectra in infants during sevoflurane wash-out  M.R.J. Sury, A. Worley, S.G. Boyd  British Journal of Anaesthesia  Volume 112, Issue 4, Pages 686-694 (April 2014) DOI: 10.1093/bja/aet409 Copyright © 2014 The Author(s) Terms and Conditions

Fig 1 Typical raw EEG signal showing change in amplitude over time. EEG recording from two channels (F3 and CP3) in an infant older than 52 weeks PMA. Vertical tick marks are 5 s apart. SO, time sevoflurane turned off; AB, time awakening began. Time difference between T1 and T2 was approximately 16 min. ↕, amplitude scale of 100 µV. Note that low frequency oscillations (approximately 2 Hz) can be seen throughout washout even up to a few seconds before awakening (examples are marked by arrows). British Journal of Anaesthesia 2014 112, 686-694DOI: (10.1093/bja/aet409) Copyright © 2014 The Author(s) Terms and Conditions

Fig 2 Typical EEG power spectral density in two infants during anaesthesia. Each graph has mean (solid line) and median (dotted line) with ±sd error bars, of the power density of 10 epochs (1 min) recorded from a centro-parietal channel before sevoflurane was turned off. x-axis scale is 1–20 Hz and y-axis scale is 0–100 µV2 Hz−1. Note that most power lies in frequencies <5Hz. In older infants (>52 weeks PMA), there was appreciable power in frequencies between 5 and 20 Hz. The mean power in a frontal channel is shown for comparison (dashed line). British Journal of Anaesthesia 2014 112, 686-694DOI: (10.1093/bja/aet409) Copyright © 2014 The Author(s) Terms and Conditions

Fig 3 Change in band power during emergence. Mean (filled circle, with 95% confidence intervals error bars) and median (open circle) decrease in band powers from anaesthesia until just before awakening in (a) infants younger and (b) infants older than 52 weeks PMA. British Journal of Anaesthesia 2014 112, 686-694DOI: (10.1093/bja/aet409) Copyright © 2014 The Author(s) Terms and Conditions

Fig 4 Change in geometric mean band power during emergence. Mean decrease in geometric mean (filled circle, with 95% confidence intervals error bars) band power from anaesthesia until just before awakening in (a) infants younger and (b) infants older than 52 weeks PMA. Difference in geometric mean is a ratio without units (i.e. ratio of 1=no difference). British Journal of Anaesthesia 2014 112, 686-694DOI: (10.1093/bja/aet409) Copyright © 2014 The Author(s) Terms and Conditions

Fig 5 Progression of EEG power in 5–20 Hz frequency band. Graphs show data from individual infants (a) younger and (b) older than 52 weeks PMA. Power units are microvolts squared and the scale is logarithmic. Epoch=6 s. British Journal of Anaesthesia 2014 112, 686-694DOI: (10.1093/bja/aet409) Copyright © 2014 The Author(s) Terms and Conditions

Fig 6 EEG power in 5–20 Hz frequency band vs age during anaesthesia. Scatter plot of age (weeks PMA) vs EEG P5–20 Hz during anaesthesia. P5–20 Hz=mean band power (5–20 Hz) during 10 sequential epochs during steady sevoflurane anaesthesia after surgery. Note that the y-axis has a logarithmic scale. British Journal of Anaesthesia 2014 112, 686-694DOI: (10.1093/bja/aet409) Copyright © 2014 The Author(s) Terms and Conditions