Rapid Simulation of P Values for Product Methods and Multiple-Testing Adjustment in Association Studies S.R. Seaman, B. Müller-Myhsok The American Journal.

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Rapid Simulation of P Values for Product Methods and Multiple-Testing Adjustment in Association Studies S.R. Seaman, B. Müller-Myhsok The American Journal of Human Genetics Volume 76, Issue 3, Pages 399-408 (March 2005) DOI: 10.1086/428140 Copyright © 2005 The American Society of Human Genetics Terms and Conditions

Figure 1 For 1,034 SNPs in the 10-Mb region, the -log10P values for individual-SNP Armitage tests (top), for the TPM on a window of 11 SNPs (middle), and for MLA tests on a window of 11 SNPs (bottom). Dotted lines indicate the Bonferroni-adjusted 5% and 1% significance thresholds. The American Journal of Human Genetics 2005 76, 399-408DOI: (10.1086/428140) Copyright © 2005 The American Society of Human Genetics Terms and Conditions