Palisaded neutrophilic and granulomatous dermatitis associated with limited systemic sclerosis Basil M. Hantash, MD, PhD, David Chiang, Sabine Kohler,

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Presentation transcript:

Palisaded neutrophilic and granulomatous dermatitis associated with limited systemic sclerosis Basil M. Hantash, MD, PhD, David Chiang, Sabine Kohler, MD, David Fiorentino, MD, PhD Journal of the American Academy of Dermatology Volume 58, Issue 4, Pages 661-664 (April 2008) DOI: 10.1016/j.jaad.2007.09.019 Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Histologic sections from a 4-mm punch biopsy of the forehead showed mixed interstitial inflammatory infiltrate that affected entire dermis and extended into fat and subjacent skeletal muscle (A). Histiocytes aggregated into noncaseating granulomata (B). Histiocytes and lymphocytes admixed with scattered neutrophils infiltrated between collagen bundles (C). No well-developed foci of degenerated collagen were present. (A to C, Hematoxylin-eosin stain; original magnifications: A, ×40; B, ×100; C, ×400.) Journal of the American Academy of Dermatology 2008 58, 661-664DOI: (10.1016/j.jaad.2007.09.019) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions