Development and Validation of a Preanalytic Procedure for Performing the cobas HPV Test in SurePath Preservative Fluid Mark D. Krevolin, David Hardy,

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Presentation transcript:

Development and Validation of a Preanalytic Procedure for Performing the cobas HPV Test in SurePath Preservative Fluid Mark D. Krevolin, David Hardy, Jim Pane, Shagufta Aslam, Catherine M. Behrens The Journal of Molecular Diagnostics Volume 19, Issue 2, Pages 288-294 (March 2017) DOI: 10.1016/j.jmoldx.2016.10.003 Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

Figure 1 Recovery of cobas HPV results from archived cervical specimens collected in SurePath preservative fluid: non-HPV16/HPV18 high-risk (HR) HPV specimens (A), HPV16 specimens (B), HPV18 specimens (C), and β-globin as a control in all specimens (D). The dashed arrows represent cutoff values for positive results, and were determined to be 40.0, 40.5, and 40.0 for channels 1 (A), 2 (B), and 3 (C), respectively. Asterisks indicate negative result (CT > 55); no CT value was produced. The Journal of Molecular Diagnostics 2017 19, 288-294DOI: (10.1016/j.jmoldx.2016.10.003) Copyright © 2017 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions