Localization of a Gene for Molybdenum Cofactor Deficiency, on the Short Arm of Chromosome 6, by Homozygosity Mapping Adel Shalata, Hanna Mandel, Jochen.

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Localization of a Gene for Molybdenum Cofactor Deficiency, on the Short Arm of Chromosome 6, by Homozygosity Mapping Adel Shalata, Hanna Mandel, Jochen Reiss, Raymonde Szargel, Annick Cohen-Akenine, Claude Dorche, Marie-Therese Zabot, Albert Van Gennip, Nico Abeling, Moshe Berant, Nadine Cohen The American Journal of Human Genetics Volume 63, Issue 1, Pages 148-154 (July 1998) DOI: 10.1086/301916 Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 1 Pedigrees of the two MoCoD kindreds. Kindreds 1 and 2 were consanguineous. Blood samples (or fibroblast cell lines [see Subjects and Methods]) and genotypes were obtained from all numbered individuals. Numbers within a circle or a square correspond to the number of siblings. Altogether we had access to DNA samples from 5 patients and 24 healthy subjects. The American Journal of Human Genetics 1998 63, 148-154DOI: (10.1086/301916) Copyright © 1998 The American Society of Human Genetics Terms and Conditions

Figure 2 Haplotype analysis, on chromosome 6p21, of MoCoD kindreds 1 and 2. Only key subjects are shown. Telomeric to centromeric markers are arranged from top to bottom. The linked haplotype is boxed. The shaded area corresponds to segments of haplotypes shared between healthy individual 5139 and affected individual 5140. Alleles in parenthesis were inferred. In family 2, marker D6S1562 was technically unsatisfactory and is not shown. The American Journal of Human Genetics 1998 63, 148-154DOI: (10.1086/301916) Copyright © 1998 The American Society of Human Genetics Terms and Conditions