Identifying and validating biomarkers for Alzheimer's disease

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Presentation transcript:

Identifying and validating biomarkers for Alzheimer's disease Christian Humpel Trends in Biotechnology Volume 29, Issue 1, Pages 26-32 (January 2011) DOI: 10.1016/j.tibtech.2010.09.007 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 The principal steps necessary for AD biomarker discovery (left flowchart) and for routine analysis of CSF samples (right flowchart). Similar steps are shown in red boxes. Only a good clinical diagnosis is the basis for statistical analysis of biomarker discovery. To date, laboratory diagnosis only supports the clinical diagnosis, which cannot be regarded as a stand-alone diagnostic tool. Trends in Biotechnology 2011 29, 26-32DOI: (10.1016/j.tibtech.2010.09.007) Copyright © 2010 Elsevier Ltd Terms and Conditions