Primary Sclerosing Cholangitis: Diagnosis, Prognosis, and Management

Slides:



Advertisements
Similar presentations
Diagnosis of Autoimmune Pancreatitis: The Mayo Clinic Experience
Advertisements

The Role of Psychosocial Care in Adapting to Health Care Reform
Abnormal Liver Tests and Fatty Liver on Ultrasound
Incorrect Calculation and Inappropriate Interpretation: Accuracy of International Guidelines for Identifying Significant Fibrosis in e Antigen–Negative.
Noncardiac Chest Pain Clinical Gastroenterology and Hepatology
Diagnosis of Autoimmune Pancreatitis: The Mayo Clinic Experience
Volume 145, Issue 3, Pages (September 2013)
CGH Receives High Impact Factor
Pichamol Jirapinyo, Christopher C. Thompson 
Coordinating Care in Patients With Cirrhosis
Biliary Stricture and Negative Cytology: What Next?
A Shocking Cystory Clinical Gastroenterology and Hepatology
Todd H. Baron, MD, Thomas C. Smyrk, MD 
Management Post-ERCP Removal of Stone in a 76-Year-Old Debilitated Man: Does He Need Cholecystectomy?  James Y.W. Lau, Joseph J.Y. Sung  Clinical Gastroenterology.
Dietary Counseling Versus Dietary Supplements for Malnutrition in Chronic Pancreatitis: A Randomized Controlled Trial  Siddharth Singh, Shallu Midha,
Phillip S. Ge, MD, Bruce A. Runyon, MD 
Diffuse Gastric Wall Thickening: Appearances Can Be Deceptive
Stephen A. Harrison, MD, FACP  Clinical Gastroenterology and Hepatology 
Amnon Sonnenberg, MD, MSc, Brent Y. Lee, MD 
Many Patients With Primary Sclerosing Cholangitis and Increased Serum Levels of Carbohydrate Antigen 19-9 Do Not Have Cholangiocarcinoma  Emmanouil Sinakos,
Judy A. Trieu, Mohammad Bilal, Ali Hashmi 
Endocuff to Improve Adenoma Detection: Supported by Low-Quality Evidence or Not Supported by High-Quality Evidence?  Yao Zhang, MD, Sheng-Bing Zhao, MD 
Giant Cell Tumor of the Common Bile Duct
Reverse Double-Wire Cannulation of the Pancreatic Duct
Pancreaticobiliary Maljunction
Pancreatic Duct Drainage for the Treatment of a Huge Pancreatic Cyst Associated With Autoimmune Pancreatitis  Hiroyuki Matsubayashi, Toru Matsui, Hiroyuki.
Interpreting Hepatitis B Surface Antigen Levels: Useful Clinical Test or Just Another Confusing Assay?  Brian J. McMahon, MD, Brenna C. Simons, PhD  Clinical.
Activity-Based Costing and Management in a Hospital-Based GI Unit
Endoscopic Therapy for Barrett's Esophagus
Recurrent Jejunal Intussusception Caused by Heterotopic Pancreas Mass
Cholangioscopy by Using Narrow-Band Imaging and Transpapillary Radiotherapy for Mucin-Producing Bile Duct Tumor  Xin–Liang Lu, Takao Itoi, Kensuke Kubota 
Obstructive Jaundice Caused by Intraductal Hepatocellular Carcinoma
Abnormal Liver Tests and Fatty Liver on Ultrasound
Gastroenterology in a New Era of Accountability: Part 2
Inflammatory Bowel Disease Is Associated With Poor Outcomes of Patients With Primary Sclerosing Cholangitis  Jing Hieng Ngu, Richard Blair Gearry, Andrew.
New Models of Gastroenterology Practice
Ramesh Kumar, Masiullah, Pintu Kumar Singh 
Vikram A. Sahni, Koenraad J. Mortele 
Dushyant Singh, Reetu Singh, Wendell K. Clarkston 
Colon Neoplasms Develop Early in the Course of Inflammatory Bowel Disease and Primary Sclerosing Cholangitis  Erin W. Thackeray, Phunchai Charatcharoenwitthaya,
Clinical Features, Response to Treatment, and Outcomes of IgG4-Related Sclerosing Cholangitis  Atsushi Tanaka, Susumu Tazuma, Kazuichi Okazaki, Takahiro.
Peter Bytzer  Clinical Gastroenterology and Hepatology 
Mark Topazian, Thomas E. Witzig, Thomas C. Smyrk, Jose S
Volume 146, Issue 2, Pages (February 2014)
Primary Sclerosing Cholangitis and Disease Distribution in Inflammatory Bowel Disease  Aoibhlinn O'Toole, Alaa Alakkari, Denise Keegan, Glen Doherty, Hugh.
Effects of Different Coping Strategies on Physical and Mental Health of Patients With Irritable Bowel Syndrome  Lilian Dindo, PhD  Clinical Gastroenterology.
Alan Bonder, MD, Nezam H. Afdhal, MD 
Suna Yapali, MD, Anna S. Lok, MD, FRCP 
Cyrus Piraka, Raj J. Shah, Nida S. Awadallah, Daniel A. Langer, Yang K
Volume 151, Issue 4, Pages (October 2016)
All Wired Up: Migration of Endovascular Coils to the Common Bile Duct
Nicolas Williet, William J. Sandborn, Laurent Peyrin–Biroulet 
Asymptomatic Dilatation of the Intrahepatic Biliary Tree Due to Thrombosed Pericholedochal Varices (Portal Biliopathy)  Junichi Shindoh, Kiyoshi Hasegawa,
Common Bile Duct Carcinoid Mimicking the Clinical, EUS, and ERCP Findings of Cholangiocarcinoma: A Rare but Potentially Curable Cause of Obstructive Jaundice 
A 27-Year-Old Woman With Constipation: Diagnosis and Treatment
Cost Effective Therapy for Sphincter of Oddi Dysfunction
Minimal-Change Esophagitis on Narrow-Band Imaging
Patrick Yachimski, William P. Puricelli, Norman S. Nishioka 
A 42–Year–Old Woman With a New Diagnosis of Sclerosing Cholangitis
Coagulation in Liver Disease: A Guide for the Clinician
Industry Payments to Gastroenterologists Across the United States
Issue Highlights Clinical Gastroenterology and Hepatology
Issue Highlights Clinical Gastroenterology and Hepatology
Medical Therapy for Refractory Pediatric Crohn’s Disease
Challenges of NIH Funding for Young Investigators: How the AGA Is Filling the Gap via the AGA Research Foundation  Timothy C. Wang, Rhonda F. Souza  Clinical.
Thomas G. Cotter, John S. Van Arnam, John A. Schaffner 
The Role of Psychosocial Care in Adapting to Health Care Reform
Reduced Coffee Consumption Among Individuals With Primary Sclerosing Cholangitis but Not Primary Biliary Cirrhosis  Craig Lammert, Brian D. Juran, Erik.
Statin Use Is Associated With Improved Outcomes of Patients With Primary Sclerosing Cholangitis  Knut Stokkeland, Jonas Höijer, Matteo Bottai, Karin Söderberg-Löfdal,
Karanprit Singh, Prateek Chapalamadugu, Peter Malet 
Presentation transcript:

Primary Sclerosing Cholangitis: Diagnosis, Prognosis, and Management Siddharth Singh, Jayant A. Talwalkar  Clinical Gastroenterology and Hepatology  Volume 11, Issue 8, Pages 898-907 (August 2013) DOI: 10.1016/j.cgh.2013.02.016 Copyright © 2013 AGA Institute Terms and Conditions

Figure 1 Typical cholangiographic findings of PSC. (A) MRCP showing multiple strictures and dilatations of the biliary tree, affecting the intrahepatic and extrahepatic biliary tree. (B) ERCP with typical findings of pruning and beaded appearance of the biliary tree. Clinical Gastroenterology and Hepatology 2013 11, 898-907DOI: (10.1016/j.cgh.2013.02.016) Copyright © 2013 AGA Institute Terms and Conditions

Figure 2 (A) Classic onion-skin fibrosis, causing obliteration of the bile ducts in PSC. (B) Ductopenia, without onion-skinning fibrosis in small-duct PSC. Photographs courtesy of Thomas Smyrk, MD, Department of Pathology, Mayo Clinic, Rochester, MN. Clinical Gastroenterology and Hepatology 2013 11, 898-907DOI: (10.1016/j.cgh.2013.02.016) Copyright © 2013 AGA Institute Terms and Conditions