Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.107 Figure 4 Summary of primary disease interactions between the gut and brain Figure 4 | Summary of primary disease interactions between the gut and brain. Aβ, amyloid-beta; ALS, amyotrophic lateral sclerosis; ASD, autism spectrum disorder; PrPSc, prion protein scrapie. Rao, M. & Gershon, M. D. (2016) The bowel and beyond: the enteric nervous system in neurological disorders Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2016.107