Hiroki Yamada, Kazuyuki Saito, Mitsuhiko Hokari, Shuta Toru

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Brain biopsy to aid diagnosis of neuro-Behçet's disease: Case report and literature review Hiroki Yamada, Kazuyuki Saito, Mitsuhiko Hokari, Shuta Toru eNeurologicalSci Volume 8, Pages 2-4 (September 2017) DOI: 10.1016/j.ensci.2017.06.001 Copyright © 2017 The Authors Terms and Conditions

Fig. 1 a–f. Axial brain MRI. Tumefactive hyperintensity in the right frontal lobe and meninges on DWI (a), FLAIR (c), and T2-WI (f) with increased ADC values (b). Tumefactive hypointensity in the lesion on T1-WI (e), showing enhancement in the cortex, meninges, and deep subcortical area on gadolinium-enhanced T1-WI (f). g, h. Histopathology of biopsied right frontal lobe and meninges (Hematoxylin-Eosin staining). Inflammation of the meninges with intact brain parenchyma. Scale bar: 500μm (g). Inflammatory infiltration of neutrophils around the blood vessels. Scale bar: 100μm (h). DWI: diffusion-weighted image, ADC-MAP: apparent diffusion coefficient map, FLAIR: fluid-attenuated inversion recovery, T2-WI: T2-weighted imaging, T1-WI: T1-weighted imaging, Gd-enhanced T1-WI: gadolinium-enhanced T1-WI. eNeurologicalSci 2017 8, 2-4DOI: (10.1016/j.ensci.2017.06.001) Copyright © 2017 The Authors Terms and Conditions