Serial Measurements of Mesothelioma Serum Biomarkers in Asbestos-Exposed Individuals: A Prospective Longitudinal Cohort Study  Kevin Hollevoet, MSc, Joris.

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Serial Measurements of Mesothelioma Serum Biomarkers in Asbestos-Exposed Individuals: A Prospective Longitudinal Cohort Study  Kevin Hollevoet, MSc, Joris Van Cleemput, MD, Joël Thimpont, MD, Paul De Vuyst, MD, PhD, Lionel Bosquée, MD, Kristiaan Nackaerts, MD, PhD, Paul Germonpré, MD, PhD, Stijn Vansteelandt, PhD, Yoshiro Kishi, PhD, Joris R. Delanghe, MD, PhD, Jan P. van Meerbeeck, MD, PhD  Journal of Thoracic Oncology  Volume 6, Issue 5, Pages 889-895 (May 2011) DOI: 10.1097/JTO.0b013e31820db377 Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 1 Spearman rank correlation plots between baseline and first follow-up levels of (A) soluble mesothelin (SM) and (C) megakaryocyte potentiating factor (MPF); and between baseline and second follow-up levels of (B) SM and (D) MPF. Journal of Thoracic Oncology 2011 6, 889-895DOI: (10.1097/JTO.0b013e31820db377) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

FIGURE 2 Box plot of (A) soluble mesothelin (SM) and (B) megakaryocyte potentiating factor (MPF) levels of the 137 participants in whom a sample at baseline, follow-up visit 1 (FU 1), and follow-up visit 2 (FU 2) was available. Biomarker levels significantly increased over time, ***p < 0.001. Journal of Thoracic Oncology 2011 6, 889-895DOI: (10.1097/JTO.0b013e31820db377) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

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