Evidence-based organ allocation∗

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Evidence-based organ allocation∗ Stefanos A Zenios, PhD, Lawrence M Wein, PhD, Glenn M Chertow, MD, MPH The American Journal of Medicine Volume 107, Issue 1, Pages 52-61 (July 1999) DOI: 10.1016/S0002-9343(99)00166-7

Figure 1 Schematic representation of the Monte Carlo simulation model. The American Journal of Medicine 1999 107, 52-61DOI: (10.1016/S0002-9343(99)00166-7)

Figure 2 Survival of transplant candidates by allocation algorithm. Survival curves were estimated from the outcomes of the first simulation run using the Kaplan-Meier product limit method. Patients who were alive on the last day of the simulation run contributed right-censored observations. FCFT = first-come first-transplanted policy. The American Journal of Medicine 1999 107, 52-61DOI: (10.1016/S0002-9343(99)00166-7)

Figure 3 Survival of transplant candidates by allocation algorithm and demographic characteristics. The American Journal of Medicine 1999 107, 52-61DOI: (10.1016/S0002-9343(99)00166-7)

Figure 4 Relative increase in quality-adjusted life expectancy (QALE) by race (top panel), sex (middle panel), and age (bottom panel). The bars indicate the relative increase in quality-adjusted life expectancy compared with UNOS for each demographic group under the first-come first-transplanted (FCFT), efficiency, and distributive efficiency algorithms. In the top panel the dark bars indicate non–African-Americans and the light bars indicate African-Americans. In the middle panel the dark bars indicate men and the light bars indicate women. In the bottom panel the dark bars indicate candidates younger than 50 years old and the light bars indicate candidates older than 50 years. The error bars are 95% confidence limits. The American Journal of Medicine 1999 107, 52-61DOI: (10.1016/S0002-9343(99)00166-7)

Figure 5 Median waiting time by race (top panel), sex (middle panel), and age (bottom panel). The bars indicate the median waiting time for each demographic group under the four allocation algorithms: first-come first-transplanted (FCFT), UNOS, efficiency, and distributive efficiency. In the top panel the dark bars indicate non–African-Americans and the light bars indicate African-Americans. In the middle panel the dark bars indicate men and the light bars indicate women. In the bottom panel the dark bars indicate candidates younger than 50 years and the light bars indicate candidates older than 50 years. The error bars are 95% confidence limits. The American Journal of Medicine 1999 107, 52-61DOI: (10.1016/S0002-9343(99)00166-7)

Figure 6 Likelihood of transplantation by allocation algorithm and race, sex, and age. The likelihood of transplantation is the probability that a candidate will receive an allograft during his or her lifetime. The American Journal of Medicine 1999 107, 52-61DOI: (10.1016/S0002-9343(99)00166-7)