Copyright Pearson Prentice Hall 10-2 Cell Division Photo Credit: © CAMR/A.B. Dowsett/Science Photo Library/Photo Researchers, Inc. Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Cell Division In eukaryotes, cell division occurs in two major stages. The first stage, division of the cell nucleus, is called mitosis. The second stage, division of the cell cytoplasm, is called cytokinesis. Copyright Pearson Prentice Hall

Chromosomes Chromosomes Genetic information is passed from one generation to the next on chromosomes. Before cell division, each chromosome is duplicated, or copied.

Copyright Pearson Prentice Hall Chromosomes Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Chromosomes “Sister” chromatids refers to the two identical copies of a single chromosome. Each pair of chromatids is attached at an area called the centromere. Sister chromatids Photo Credit: © Gunther F. Bahr/AFIP/Stone Centromere Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Chromosomes When the cell divides, the chromatids separate. Each new cell gets one chromatid. The structure of a chromosome: One long continuous thread of DNA DNA wraps around proteins called histones DNA and histones form chromatin (which looks like spaghetti) during interphase Chromosomes condense tightly for mitosis. Before they are duplicated, they look like half of an X Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall The Cell Cycle Cell Cycle The cell cycle is the series of events that cells go through as they grow and divide. Interphase is the period of growth that occurs between cell divisions. Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall The Cell Cycle During the cell cycle: a cell grows prepares for division divides to form two daughter cells, each of which begins the cycle again Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall The Cell Cycle The cell cycle consists of four phases: G1 (First Gap Phase) S Phase G2 (Second Gap Phase) M Phase (mitosis) Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Mitosis Mitosis Biologists divide the events of mitosis into four phases: (PMAT) Prophase Metaphase Anaphase Telophase Copyright Pearson Prentice Hall

Events of the Cell Cycle Fill in lines 1, 3, 5, 7, 9-13, 14, 15 in your diagram of the cell cycle During the cell cycle, the cell grows, replicates its DNA, and divides into two daughter cells. DNA synthesis takes place during the S phase. Cell division takes place during the M phase. G1 and G2 are gap phases. Copyright Pearson Prentice Hall

Events of the Cell Cycle During G1, the cell (write bullets on line 2 of cell cycle) increases in size synthesizes new proteins and organelles Copyright Pearson Prentice Hall

Events of the Cell Cycle During the S phase, (write bullets on line 4 of cell cycle) chromosomes are replicated DNA synthesis takes place Once a cell enters the S phase, it usually completes the rest of the cell cycle. Copyright Pearson Prentice Hall

Events of the Cell Cycle The G2 Phase (Second Gap Phase) (write bullets on line 6 of cell cycle) organelles and molecules required for cell division are produced Once G2 is complete, the cell is ready to start the M phase—Mitosis Copyright Pearson Prentice Hall

Events of the Cell Cycle During the cell cycle, the cell grows, replicates its DNA, and divides into two daughter cells. DNA synthesis takes place during the S phase. Cell division takes place during the M phase. G1 and G2 are gap phases. Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Mitosis Interphase Grows Copies DNA Duplicates organelles Most eukaryotic cells go through a regular cycle of interphase, mitosis and cytokinesis. Mitosis has four phases: Prophase, Metaphase, Anaphase and Telophase. The events shown here are typical of animal cells. Mitosis Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Mitosis Spindle forming Prophase Chromatin condenses into chromosomes. The centrioles separate and a spindle begins to form. The nuclear envelope breaks down. Centromere Chromosomes (paired chromatids) Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Mitosis Centriole Metaphase The second phase of mitosis is metaphase. The chromosomes line up across the center of the cell. Microtubules connect the centromere of each chromosome to the poles of the spindle. Spindle Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Mitosis Anaphase Anaphase is the third phase of mitosis. The sister chromatids separate into individual chromosomes and move to opposite sides of the cell Individual chromosomes Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Mitosis Telophase Telophase is the fourth and final phase of mitosis. Chromosomes gather at opposite ends of the cell and lose their distinct shape. A new nuclear envelope forms around each cluster of chromosomes. Chromosomes begin to uncoil Spindle fibers fall apart Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall Cytokinesis During cytokinesis, the cytoplasm pinches in half. Each daughter cell has an identical set of duplicate chromosomes Copyright Pearson Prentice Hall

Can you name these phases?

Can you name these phases? 1 - Prophase 2 - Metaphase 3 - Anaphase 4 - Telophase 5 - Interphase

Copyright Pearson Prentice Hall Cytokinesis in Plants In plants, a structure known as the cell plate forms midway between the divided nuclei. Cell plate Cell wall Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall 10-2 - or - (must have QuickTake software installed on the computer you are using for this presentation) Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall 10-2 The series of events that cells go through as they grow and divide is called the cell cycle. mitosis. interphase. cytokinesis. Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall 10-2 The phase of mitosis during which the chromosomes line up across the center of the cell is prophase. metaphase. anaphase. telophase. Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall 10-2 Cytokinesis usually occurs at the same time as telophase. after telophase. during interphase. during anaphase Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall 10-2 DNA replication takes place during the S phase of the cell cycle. G1 phase of the cell cycle. G2 phase of the cell cycle. M phase of the cell cycle. Copyright Pearson Prentice Hall

Copyright Pearson Prentice Hall 10-2 During mitosis, “sister” chromatids separate from one another during telophase. interphase. anaphase. metaphase. Copyright Pearson Prentice Hall

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