Volume 55, Issue 1, Pages (July 2011)

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Volume 55, Issue 1, Pages 224-226 (July 2011) Non-invasive diagnostic imaging of hepatocellular carcinoma: Targeting cellular characterization? Alain Luciani, Laurence Baranes, Thomas Decaens, Frederic Pigneur, Alexis Laurent, Jeanne Tran-Van Nhieu, Alain Rahmouni Journal of Hepatology Volume 55, Issue 1, Pages 224-226 (July 2011) DOI: 10.1016/j.jhep.2011.01.026 Copyright © 2011 European Association for the Study of the Liver Terms and Conditions

Fig. 1 Fifty-seven-year old patient with liver cirrhosis and right lobe hepatocellular carcinoma referred for liver MRI. Transverse gradient echo (GE) in-phase T1WI (TR/TE/α; 119ms/4.8ms/70°; slice thickness 5mm) shows a 4cm peripherally located liver tumor, with high signal intensity (Arrow, A) and drop of signal intensity on out-of-phase T1WI (TR/TE/α; 119ms/2.4ms/70°; slice thickness 5mm) (Arrow, B) suggesting the presence of fat within the tumor. The tumor is iso-intense on Transverse Turbo Spin Echo (TSE) T2 WI (TR/TE/α; 2410ms/82ms/150°; slice thickness 5mm) (C), with absent visible restriction on ADC mapping (Diffusion Weighted Imaging, Arrow, D). The tumor displays mild arterial enhancement on transverse 3D VIBE (Volumetric Interpolated Breath-hold Examination) T1 WI (TR/TE/α; 3.17/1.33/20; slice thickness 3mm) (E) with washout on delayed enhancement phase (Arrow, F). A well-differentiated HCC nodule was confirmed on pathology following liver transplantation (Arrow, G). Journal of Hepatology 2011 55, 224-226DOI: (10.1016/j.jhep.2011.01.026) Copyright © 2011 European Association for the Study of the Liver Terms and Conditions