Change from baseline in global improvement, symptom severity, adequate relief, and quality of life. IBS-GIS indicates the Irritable Bowel Syndrome Global.

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Presentation transcript:

Change from baseline in global improvement, symptom severity, adequate relief, and quality of life. IBS-GIS indicates the Irritable Bowel Syndrome Global Improvement Scale; IBS-SSS, Irritable Bowel Syndrome Symptom Severity Scale; IBS-AR, Irritable Bowel Syndrome Adequate Relief; and IBS-QOL, Irritable Bowel Syndrome Quality of Life Questionnaire. Change from baseline in global improvement, symptom severity, adequate relief, and quality of life. IBS-GIS indicates the Irritable Bowel Syndrome Global Improvement Scale; IBS-SSS, Irritable Bowel Syndrome Symptom Severity Scale; IBS-AR, Irritable Bowel Syndrome Adequate Relief; and IBS-QOL, Irritable Bowel Syndrome Quality of Life Questionnaire. Values are expressed as mean change. Positive scores denote improvement. The intervention group demonstrated significantly larger between-group improvement than the comparison group in the (A) GIS at 4 weeks (1.93 vs 1.07; ES 0.55, p=0.04; n=56—primary endpoint) and 8 weeks postbaseline (1.81 vs 0.59; ES 0.63, p=0.02; n=55), and (B) SSS at 4 weeks (121.4 vs 59.6; ES 0.56, p=0.04) and 8 weeks (116.4 vs 50.0; Effect Size (Cohen's D) (ES) 0.57, p=0.03) postbaseline. No significant between-group differences were seen in the (C) AR and (D) QOL scales. Relative to baseline, all outcomes improved in both groups at 4 weeks and 8 weeks. Ather Ali et al. BMJ Open Gastroenterol 2017;4:e000164 © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.