The Importance of Genealogy in Determining Genetic Associations with Complex Traits Dina L. Newman, Mark Abney, Mary Sara McPeek, Carole Ober, Nancy J.

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The Importance of Genealogy in Determining Genetic Associations with Complex Traits Dina L. Newman, Mark Abney, Mary Sara McPeek, Carole Ober, Nancy J. Cox The American Journal of Human Genetics Volume 69, Issue 5, Pages 1146-1148 (November 2001) DOI: 10.1086/323659 Copyright © 2001 The American Society of Human Genetics Terms and Conditions

Figure 1 Results of two genome scans—one including pedigree structure (lighter bars) and one not including pedigree structure (darker bars)—for IgE (a), LDL (b), and BMI (c). The five most significant loci when structure is included (left sides) and when structure is not included (right sides) are shown. The American Journal of Human Genetics 2001 69, 1146-1148DOI: (10.1086/323659) Copyright © 2001 The American Society of Human Genetics Terms and Conditions

Figure 2 Number of significantly associated (P<.01) loci when pedigree structure is included (lighter bars) and when pedigree structure is not included (darker bars). The American Journal of Human Genetics 2001 69, 1146-1148DOI: (10.1086/323659) Copyright © 2001 The American Society of Human Genetics Terms and Conditions