The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients Yaakov Bentov, M.D., M.Sc., Navid Esfandiari, D.V.M.,

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Presentation transcript:

The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients Yaakov Bentov, M.D., M.Sc., Navid Esfandiari, D.V.M., Ph.D., H.C.L.D., Eliezer Burstein, M.D., Robert F. Casper, M.D., F.R.C.S.C. Fertility and Sterility Volume 93, Issue 1, Pages 272-275 (January 2010) DOI: 10.1016/j.fertnstert.2009.07.988 Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Mitochondrial DNA. The double-stranded circular mitochondrial genome. The allocation of genes is highlighted by their color. The site is of the common deletion is demonstrated by the arch on the lower right side of the drawing. Fertility and Sterility 2010 93, 272-275DOI: (10.1016/j.fertnstert.2009.07.988) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

Figure 2 The mitochondrial electron transport chain. The mitochondrial respiratory chain is organized in five complexes situated in the inner mitochondrial membrane. Complex I: NADH-Q oxidoreductase; complex II: succinate-Q reductase; complex III: Q-cytochrome c oxidoreductase; complex IV: cytochrome c oxidase; and complex V: ATP synthase. The central role of coenzyme Q10 (CoQ10) in both electron and proton transport is highlighted. Fertility and Sterility 2010 93, 272-275DOI: (10.1016/j.fertnstert.2009.07.988) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions