A Pilot Study of Fecal Serine-Protease Activity: A Pathophysiologic Factor in Diarrhea- Predominant Irritable Bowel Syndrome Richárd Róka, András Rosztóczy, Mathilde Leveque, Ferenc Izbéki, Ferenc Nagy, Tamás Molnár, János Lonovics, Rafael Garcia–Villar, Jean Fioramonti, Tibor Wittmann, Lionel Bueno Clinical Gastroenterology and Hepatology Volume 5, Issue 5, Pages 550-555 (May 2007) DOI: 10.1016/j.cgh.2006.12.004 Copyright © 2007 AGA Institute Terms and Conditions
Figure 1 Fecal serine-protease activity in healthy controls, IBS-C, IBS-A, IBS-D, and UC patients. Boxes extend from the 25th–75th percentiles, lines at the median show the 50th percentile; the whiskers extending above and below the boxes show the highest and lowest values. **P < .001 compared with controls. Clinical Gastroenterology and Hepatology 2007 5, 550-555DOI: (10.1016/j.cgh.2006.12.004) Copyright © 2007 AGA Institute Terms and Conditions
Figure 2 Fecal mast cell tryptase activity. See Figure 1 for a description of the groups. Boxes extend from the 25th–75th percentiles, lines at the median show the 50th percentile; the whiskers extending above and below the boxes show the highest and lowest values. Clinical Gastroenterology and Hepatology 2007 5, 550-555DOI: (10.1016/j.cgh.2006.12.004) Copyright © 2007 AGA Institute Terms and Conditions
Figure 3 Fecal pancreatic elastase-1 concentration. See Figure 1 for a description of the groups. Boxes extend from the 25th–75th percentiles, lines at the median show the 50th percentile; the whiskers extending above and below the boxes show the highest and lowest values. Clinical Gastroenterology and Hepatology 2007 5, 550-555DOI: (10.1016/j.cgh.2006.12.004) Copyright © 2007 AGA Institute Terms and Conditions
Figure 4 Fecal human SLPI concentration. See Figure 1 for a description of the groups. Boxes extend from the 25th–75th percentiles, lines at the median show the 50th percentile; the whiskers extending above and below the boxes show the highest and lowest values. Clinical Gastroenterology and Hepatology 2007 5, 550-555DOI: (10.1016/j.cgh.2006.12.004) Copyright © 2007 AGA Institute Terms and Conditions