Role of Colonic Fermentation in the Perception of Colonic Distention in Irritable Bowel Syndrome and Functional Bloating  Michele Di Stefano, Emanuela Miceli, Antonio Missanelli, Samanta Mazzocchi, Paola Tana, Gino Roberto Corazza  Clinical Gastroenterology and Hepatology  Volume 4, Issue 10, Pages 1242-1247 (October 2006) DOI: 10.1016/j.cgh.2006.07.004 Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 1 Design of the study. (A) Rectal barostat test with lactulose solution. (B) Rectal barostat test with electrolyte solution. Clinical Gastroenterology and Hepatology 2006 4, 1242-1247DOI: (10.1016/j.cgh.2006.07.004) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 2 Time H2 breath excretion mean curves in IBS-C, IBS-D, and FB patients and healthy volunteers. Clinical Gastroenterology and Hepatology 2006 4, 1242-1247DOI: (10.1016/j.cgh.2006.07.004) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 3 Perception and discomfort thresholds before and after electrolyte solution in IBS patients, FB patients, and healthy volunteers. Horizontal lines indicate mean value. Clinical Gastroenterology and Hepatology 2006 4, 1242-1247DOI: (10.1016/j.cgh.2006.07.004) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 4 Modifications of perception and discomfort thresholds after lactulose in IBS patients, FB patients, and healthy volunteers. Open circles indicate low hydrogen breath excretors; closed circles indicate high hydrogen breath excretors. Clinical Gastroenterology and Hepatology 2006 4, 1242-1247DOI: (10.1016/j.cgh.2006.07.004) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions

Figure 5 Perception and discomfort thresholds before and after lactulose in healthy volunteers and patients with low hydrogen breath excretion or high hydrogen breath excretion. Horizontal lines indicate mean value. Clinical Gastroenterology and Hepatology 2006 4, 1242-1247DOI: (10.1016/j.cgh.2006.07.004) Copyright © 2006 American Gastroenterological Association (AGA) Institute Terms and Conditions