Does the Hematopoietic Cell Transplantation Specific Comorbidity Index Predict Transplant Outcomes? A Validation Study in a Large Cohort of Umbilical.

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Does the Hematopoietic Cell Transplantation Specific Comorbidity Index Predict Transplant Outcomes? A Validation Study in a Large Cohort of Umbilical Cord Blood and Matched Related Donor Transplants Navneet S. Majhail, Claudio G. Brunstein, Sarah McAvoy, Todd E. DeFor, Ahmed Al-Hazzouri, Daniela Setubal, Mukta Arora, Chap T. Le, John E. Wagner, Daniel J. Weisdorf Biology of Blood and Marrow Transplantation Volume 14, Issue 9, Pages 985-992 (September 2008) DOI: 10.1016/j.bbmt.2008.06.008 Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Distribution of comorbidities in MA (N = 150) and NMA (N = 223) hematopoietic cell transplant recipients (Y-axis represents percentage of patients within the cohort with specific comorbidities). Biology of Blood and Marrow Transplantation 2008 14, 985-992DOI: (10.1016/j.bbmt.2008.06.008) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Cumulative incidence of NRM by conditioning regimen and donor source for HCT-CI scores (1-year rates are indicated in brackets; MRD, matched related donor; UCB, umbilical cord blood; MA, myeloablative conditioning; NMA, nonmyeloablative conditioning). Biology of Blood and Marrow Transplantation 2008 14, 985-992DOI: (10.1016/j.bbmt.2008.06.008) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 3 Probability of OS by conditioning regimen and donor source for HCT-CI scores (2-year rates are indicated in brackets; MRD, matched related donor; UCB, umbilical cord blood; MA, myeloablative conditioning; NMA, nonmyeloablative conditioning). Biology of Blood and Marrow Transplantation 2008 14, 985-992DOI: (10.1016/j.bbmt.2008.06.008) Copyright © 2008 American Society for Blood and Marrow Transplantation Terms and Conditions