Pralidoxime for organophosphate poisoning

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Presentation transcript:

Pralidoxime for organophosphate poisoning Peter Eyer, Nicholas Buckley The Lancet Volume 368, Issue 9553, Pages 2110-2111 (December 2006) DOI: 10.1016/S0140-6736(06)69843-7 Copyright © 2006 Elsevier Ltd Terms and Conditions

Figure Calculated pralidoxime plasma concentration, two-dose regimen Calculated for 50-kg person. High dose=2-g bolus over 30 min, then continuous infusion of 1 g/h for 48 h, then 1 g/h every 4 h. Low dose=2-g bolus over 30 min, then 1 g/h every 4 h. The Lancet 2006 368, 2110-2111DOI: (10.1016/S0140-6736(06)69843-7) Copyright © 2006 Elsevier Ltd Terms and Conditions