Deubiquitination of Lys63-Linkage by a CYLD UBP

Slides:



Advertisements
Similar presentations
Recognizing Protein-Ligand Binding Sites by Global Structural Alignment and Local Geometry Refinement Ambrish Roy, Yang Zhang Structure Volume 20, Issue.
Advertisements

Javed A. Khan, Ben M. Dunn, Liang Tong  Structure 
Ross Alexander Robinson, Xin Lu, Edith Yvonne Jones, Christian Siebold 
Volume 16, Issue 11, Pages (November 2008)
Adding Specificity to Artificial Transcription Activators
Identification of Phe187 as a Crucial Dimerization Determinant Facilitates Crystallization of a Monomeric Retroviral Integrase Core Domain  Meytal Galilee,
Meiosis: A PRDM9 Guide to the Hotspots of Recombination
Deubiquitination of Lys63-Linkage by a CYLD UBP
Solution Structure of the U11-48K CHHC Zinc-Finger Domain that Specifically Binds the 5′ Splice Site of U12-Type Introns  Henning Tidow, Antonina Andreeva,
Volume 18, Issue 8, Pages (August 2010)
Protein Kinase C Regulation: C1 Meets C-tail
The Architecture of Restriction Enzymes
Chromosomal DNA Replication on a Protein “Chip”
Jean–Michel Pawlotsky, Stéphane Chevaliez, John G. McHutchison 
Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD
Bypassing Translation Initiation
Volume 24, Issue 11, Pages (November 2016)
Volume 15, Issue 2, Pages (February 2007)
Riboswitches: Fold and Function
Ins and Outs of Kinase DFG Motifs
Volume 15, Issue 4, Pages (April 2007)
Ross Alexander Robinson, Xin Lu, Edith Yvonne Jones, Christian Siebold 
Structure of the UBA Domain of Dsk2p in Complex with Ubiquitin
Volume 29, Issue 4, Pages (February 2008)
Multiple Conformations of F-actin
Seisuke Yamashita, Kozo Tomita  Structure 
Volume 133, Issue 1, Pages (April 2008)
Volume 17, Issue 6, Pages (June 2009)
Error-Prone DNA Polymerases
Volume 17, Issue 6, Pages (June 2009)
Volume 15, Issue 2, Pages (February 2007)
Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair  Takashi Ochi, Xiaolong.
PcrA Helicase, a Prototype ATP-Driven Molecular Motor
Caught on Camera: Intermediates of Ribosome Recycling
Volume 25, Issue 11, Pages e4 (November 2017)
Volume 25, Issue 11, Pages e3 (November 2017)
Crystal Structure of the p53 Core Domain Bound to a Full Consensus Site as a Self- Assembled Tetramer  Yongheng Chen, Raja Dey, Lin Chen  Structure  Volume.
Volume 23, Issue 1, Pages (January 2015)
A Different Look for AB5 Toxins
The Unmasking of Telomerase
Volume 14, Issue 11, Pages (November 2006)
Volume 17, Issue 10, Pages (October 2009)
An open and closed case for all polymerases
Crystal Structures of the BAR-PH and PTB Domains of Human APPL1
Remodeling KRAS Structure
A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity  Nadine L. Samara, Alison E. Ringel, Cynthia Wolberger 
Volume 14, Issue 4, Pages (April 2006)
Volume 19, Issue 5, Pages (May 2011)
Huiying Li, Michael R. Sawaya, F. Robert Tabita, David Eisenberg 
Volume 13, Issue 10, Pages (October 2005)
DNA Synthesis across an Abasic Lesion by Human DNA Polymerase ι
Mapping the Deubiquitination Module within the SAGA Complex
Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with an Unusual Mode of Binding  David J. Sidote, Christopher.
Robert S. Magin, Glen P. Liszczak, Ronen Marmorstein  Structure 
Volume 16, Issue 11, Pages (November 2008)
Michael M. Brent, Ruchi Anand, Ronen Marmorstein  Structure 
Clemens C. Heikaus, Jayvardhan Pandit, Rachel E. Klevit  Structure 
Network of Dynamically Important Residues in the Open/Closed Transition in Polymerases Is Strongly Conserved  Wenjun Zheng, Bernard R. Brooks, Sebastian.
Two Pathways Mediate Interdomain Allosteric Regulation in Pin1
Structural Basis of RIP1 Inhibition by Necrostatins
Structural Basis of Proline-Proline Peptide Bond Specificity of the Metalloprotease Zmp1 Implicated in Motility of Clostridium difficile  Magdalena Schacherl,
Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance
Volume 25, Issue 11, Pages e3 (November 2017)
Volume 13, Issue 5, Pages (May 2005)
Brett K. Kaiser, Matthew C. Clifton, Betty W. Shen, Barry L. Stoddard 
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases  Scott Bailey, Richard A. Wing, Thomas A. Steitz 
Yogesh K. Gupta, Deepak T. Nair, Robin P. Wharton, Aneel K. Aggarwal 
Alternate Modes of Cognate RNA Recognition by Human PUMILIO Proteins
Robert S. Magin, Glen P. Liszczak, Ronen Marmorstein  Structure 
Volume 14, Issue 8, Pages (August 2006)
Presentation transcript:

Deubiquitination of Lys63-Linkage by a CYLD UBP Yigong Shi  Structure  Volume 16, Issue 3, Pages 338-340 (March 2008) DOI: 10.1016/j.str.2008.02.001 Copyright © 2008 Elsevier Ltd Terms and Conditions

Figure 1 Structural Features of a CYLD UBP Domain The catalytic core domain of CYLD is colored blue, with the β12/β13 loop highlighted in magenta. The zinc-binding B-box domain is indicated by red circle. The structure of USP7/HAUSP, shown in gray, is aligned with CYLD. The three conserved subdomains (Thumb, Palm, and Fingers) of a UBP are labeled and schematically separated by cyan lines. Structure 2008 16, 338-340DOI: (10.1016/j.str.2008.02.001) Copyright © 2008 Elsevier Ltd Terms and Conditions