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Leflunomide in GCA Adizie Diamantopoulos Case series: Difficult-to-treat GCA in 9 patients Partial/complete response achieved in 21/23 Well tolerated, decrease in inflammatory markers, decreased steroid doses Diamantopoulos Case series: refractory GCA in 11 patients 12.4 mg/dL (CI 95% 0.7-25.5, P = .06) reduction in CRP 6.6 mg (CI 95% 2.8-10.3, P < .01) reduction in prednisolone dose Adizie T, et al. Int J Clin Pract. 2012;66:906-909.[7] Diamantopoulos AP, et al. Biomed Res Int. 2013;2013:120638.[14]