Annual Meeting 9th December 2015

Mark Foster Mark.foster@mdsas.com Replace this photo with your own by going to Insert  Photo  Picture from File.

2015/16 Annual Report

Total recorded usage 28,260,840 Grams

Estimated recorded cost £847,825,000

Recorded yearly increase Grams % Increase 2012/13 3,185,000 11% 2013/14 3,675000 15% 2014/15 4,275,000 16% 2015/16 4,577000 6%

Recorded yearly usage

CMU sales comparison June 2015 – May 2016 Intravenous 88% Sub-cutaneous 90% Total Vs. CMU sales

Number of patients treated by year

Number of patients treated by region

Yearly Usage by Region

Average patient usage by region

Number of patients treated by Speciality

Yearly Usage by Speciality

Average patient usage by speciality

Average patient usage - Immunology Condition 15/16 LY PID 1,206,000 +8% Secondary 285,000 +24% Specific 53,477 +10%

Average patient usage – Neurology Condition 15/16 LY CIDP 910,000 +5% MMN 454,000 +10% MG 173,000 - Inflammatory myopathies 107,000 GB 137,000 +19%

Average patient usage – Haematology Condition 15/16 LY ITP - Acute 263,000 +17% ITP – Persistent 67,000 +21%

Yearly usage by product type

Yearly intravenous product usage

Yearly subcutaneous product usage

Grey Usage 2011/12 – 2015-16 Year 2011/12 2012/13 2013/14 20141/15 2015/16 Usage 143,870 158,951 184,498 204,944 208,922

Grey patients and outcomes2011/12 – 2015-16 Year 2011/12 2012/13 2013/14 2014/15 2015/16 Grey Requests 812 911 908 831 849 Outcomes n/a 271 245 235 247 Percentage 30% 27% 28% 29%

Grey Usage 2015-16

Grey Usage 2015-16 561 Grey unlisted requests since Jan 2015 4 Centres are responsible for half of these requests 10-20% of Grey unlisted are incorrectly registered Tetanus – Most common incorrect registration

Outcomes recorded by speciality

Outcomes recorded by conditions

Outcomes recorded – Top region

Summary Increase in reported usage starting to level off 2015/16 saw highest capture Vs CMU sales Further database improvements made to support the commissioning of Ig NHS England utilising the database to develop policy Database can help to identify cost saving opportunities Focus on the collection of outcomes Address incorrect Ig requests Scotland and Northern Ireland now using the database

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