Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema Dagmar Simon, MD, Jennifer Wittwer, MD, Ganna Kostylina,

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Presentation transcript:

Alefacept (lymphocyte function-associated molecule 3/IgG fusion protein) treatment for atopic eczema Dagmar Simon, MD, Jennifer Wittwer, MD, Ganna Kostylina, PhD, Urs Buettiker, MD, Hans-Uwe Simon, MD, PhD, Nikhil Yawalkar, MD Journal of Allergy and Clinical Immunology Volume 122, Issue 2, Pages 423-424 (August 2008) DOI: 10.1016/j.jaci.2008.06.010 Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Reduced skin inflammation with alefacept therapy. A, Reduction of the EASI. Asterisks indicate P values of less than .05. B, Clinical response. C, Number of skin inflammatory cells. P values of significant differences are indicated. ECP, Eosinophil cationic protein. D, Quantification of cytokine-expressing CD4+ and CD8+ cells in lesional skin. E, Representative original images of data presented in Fig 1, D (original magnification ×1000). Journal of Allergy and Clinical Immunology 2008 122, 423-424DOI: (10.1016/j.jaci.2008.06.010) Copyright © 2008 American Academy of Allergy, Asthma & Immunology Terms and Conditions