Analgesic and Sedative Effects of Melatonin in Temporomandibular Disorders: A Double-Blind, Randomized, Parallel-Group, Placebo-Controlled Study Liliane.

Slides:

Advertisements

Similar presentations

Treatment of postherpetic neuralgia: a review of therapeutic options Charles E. Argoff, MD, Nathaniel Katz, MD, Miroslav Backonja, MD Journal of Pain and.

Advertisements

Validation of the Wisconsin Brief Pain Questionnaire in a Multilingual South African Population Noko Mphahlele, MSc, Duncan Mitchell, PhD, Peter Kamerman,

Spinal Cord and Peripheral Nerve Stimulation Techniques for Neuropathic Pain Oscar A. de Leon-Casasola, MD Journal of Pain and Symptom Management Volume.

Comparison of the Constipation Assessment Scale and Plain Abdominal Radiography in the Assessment of Constipation in Advanced Cancer Patients Kittiphon.

Management of Phantom Pain with a Textile, Electromagnetically-Acting Stump Liner: A Randomized, Double-Blind, Crossover Study Uwe Kern, MD, Bernd Altkemper,

Oropharyngeal Mucositis Pain Treatment with Transdermal Buprenorphine in Patients After Allogeneic Stem Cell Transplantation Samuel Vokurka, MD, PhD

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Shuangbai San for Treating Primary Liver Cancer Patients With Cancer Pain Xiaowei.

Chronic Pain Management in Older Adults: Special Considerations

Patient-Reported Outcomes as a Component of the Primary Endpoint in a Double-Blind, Placebo-Controlled Trial in Advanced Pancreatic Cancer S. Gail Eckhardt,

Pain, Demographics, and Clinical Characteristics in Persons Who Received Hospice Care in the United States Scott A. Strassels, PharmD, PhD, BCPS, David.

Wen Jing Chung, MD, MS, Gregory H. Pharo, DO

The Public Health Strategy for Palliative Care

Chronic Pain Management in Older Adults: Special Considerations

Opioids for Cancer Breakthrough Pain: A Pilot Study Reporting Patient Assessment of Time to Meaningful Pain Relief Giovambattista Zeppetella, FRCP Journal.

Why Now? Timing and Circumstances of Hastened Deaths

Jennifer S. Albrecht, PhD, Jessina C. McGregor, PhD, Erik K

Reliability, Validity, and Responsiveness of the Daily Sleep Interference Scale Among Diabetic Peripheral Neuropathy and Postherpetic Neuralgia Patients

A Double-Blind, Placebo-Controlled, Crossover Pilot Trial With Extension Using an Oral Mucosal Cannabinoid Extract for Treatment of Chemotherapy-Induced.

Efficacy and Safety of the Seven-Day Buprenorphine Transdermal System in Opioid- Naïve Patients with Moderate to Severe Chronic Low Back Pain: An Enriched,

What Palliative Care-Related Problems Do Patients Experience at HIV Diagnosis? A Systematic Review of the Evidence Victoria M. Simms, MSc, Irene J. Higginson,

Caffeine as an Adjuvant Therapy to Opioids in Cancer Pain: A Randomized, Double- Blind, Placebo-Controlled Trial Sang-Yeon Suh, MD, PhD, Youn Seon Choi,

Oropharyngeal Mucositis Pain Treatment with Transdermal Buprenorphine in Patients After Allogeneic Stem Cell Transplantation Samuel Vokurka, MD, PhD

Patient-Reported Pressure Ulcer Pain: A Mixed-Methods Systematic Review Claudia Gorecki, MSc, S. José Closs, PhD, RGN, Jane Nixon, PhD, RN, Michelle Briggs,

Eduardo Bruera, MD, Raul Sala, MD, Odette Spruyt, MD, J

Geographic Variation in Hospice Use in the United States in 2002

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Shuangbai San for Treating Primary Liver Cancer Patients With Cancer Pain Xiaowei.

Double-Blind, Placebo-Controlled Trial of Lamotrigine in Combination with Other Medications for Neuropathic Pain Marianne Silver, MS, David Blum, MD,

Development and Initial Validation of the Three-Levels-of-Needs Questionnaire for Self- Assessment of Palliative Needs in Patients with Cancer Anna Thit.

A randomized, double-blind, crossover study of the use of transcutaneous spinal electroanalgesia in patients with pain from chronic critical limb ischemia

Jean-Pierre Van Buyten, MD Journal of Pain and Symptom Management

Tetrodotoxin for Moderate to Severe Cancer Pain: A Randomized, Double Blind, Parallel Design Multicenter Study Neil A. Hagen, MD, FRCPC, Patrick du Souich,

A Systematic Review of Topical Treatments to Control the Odor of Malignant Fungating Wounds Cristina Mamédio da Costa Santos, RN, MsN, Cibele Andrucioli.

David Clark, PhD, Michael Wright, PhD

Redefining Appropriate Treatment Expectations

Long-Term Analgesic Effects of Transcranial Direct Current Stimulation of the Motor Cortex on Phantom Limb and Stump Pain: A Case Report Nadia Bolognini,

Treatment of Cancer Pain with Noninvasive Brain Stimulation

Integrating Palliative Care into National Policies

Jodi L. Hannan, MD, Steven M. Radwany, MD, Terry Albanese, PhD

A Pilot Randomized Controlled Trial of an Oral Care Intervention to Reduce Mucositis Severity in Stem Cell Transplant Patients Prisco Salvador, RN, MScN,

Symptom Prevalence and Management of Cancer Patients in Lebanon

Amitriptyline in the Treatment of Chemotherapy-Induced Neuropathic Symptoms Anna-Liisa Kautio, MD, Maija Haanpää, MD, PhD, Tiina Saarto, MD, PhD, Eija.

Barrie R. Cassileth, PhD, Andrew J. Vickers, PhD

A Proposed Taxonomy of Terms to Guide the Clinical Trial Recruitment Process Neil A. Hagen, MD, FRCPC, Jackson S. Wu, MD, FRCPC, Carla R. Stiles, BN

Efficacy and Side Effects of Diclofenac Patch in Treatment of Patients with Myofascial Pain Syndrome of the Upper Trapezius Lin-Fen Hsieh, MD, Chang-Zern.

Robert L. Jayes, MD, Robert M. Arnold, MD, Erik K. Fromme, MD

The Brief Fatigue Inventory: Comparison of Data Collection Using a Novel Audio Device with Conventional Paper Questionnaire Edward Pallett, PhD, Patricia.

Effects of Methylphenidate on Fatigue and Depression: A Randomized, Double-Blind, Placebo-Controlled Trial Christopher W. Kerr, MD, PhD, Julie Drake,

U.S. Hospice Benefits Journal of Pain and Symptom Management

Blinded Patient Preference for Morphine Compared to Placebo in the Setting of Chronic Refractory Breathlessness—An Exploratory Study Diana H. Ferreira,

The Spiritual Needs Assessment for Patients (SNAP): Development and Validation of a Comprehensive Instrument to Assess Unmet Spiritual Needs Rashmi K.

Armodafinil for Sarcoidosis-Associated Fatigue: A Double-Blind, Placebo-Controlled, Crossover Trial Elyse E. Lower, MD, Atul Malhotra, MD, Victoria Surdulescu,

Randomized, Double-Blind, Placebo-Controlled Trial of Oral Docusate in the Management of Constipation in Hospice Patients Yoko Tarumi, MD, Mitchell P.

Is the B12/CRP Index More Accurate Than You at Predicting Life Expectancy in Advanced Cancer Patients? Filipa Tavares, MD Journal of Pain and Symptom.

Development and Reliability Testing of the Victoria Bowel Performance Scale (BPS) G. Michael Downing, MD, Craig Kuziemsky, PhD, Mary Lesperance, PhD,

Comparative Efficacy of Oral Extended-Release Hydromorphone and Immediate- Release Hydromorphone in Patients with Persistent Moderate to Severe Pain: Two.

A Double-Blind, Randomized, Crossover Comparison Between Single-Dose and Double-Dose Immediate-Release Oral Morphine at Bedtime in Cancer Patients Ola.

Tomoyuki Kawada, MD Journal of Pain and Symptom Management

A Meta-Analysis of the Relationship Between Response Expectancies and Cancer Treatment-Related Side Effects Stephanie J. Sohl, PhD, Julie B. Schnur,

Use of the Palliative Outcome Scale in Argentina: A Cross-Cultural Adaptation and Validation Study Jorge H. Eisenchlas, MD, MSc, Richard Harding, BSc,

Effects of Prophylactic Subcutaneous Fentanyl on Exercise-Induced Breakthrough Dyspnea in Cancer Patients: A Preliminary Double-Blind, Randomized, Controlled.

Using the Symptom Monitor in a Randomized Controlled Trial: The Effect on Symptom Prevalence and Severity Johanna Hoekstra, MA, Rien de Vos, PhD, Nico.

Hsien Seow, PhD, Claire F. Snyder, PhD, MHS, Richard A

Management of Phantom Pain with a Textile, Electromagnetically-Acting Stump Liner: A Randomized, Double-Blind, Crossover Study Uwe Kern, MD, Bernd Altkemper,

Amy P. Abernethy, MD Journal of Pain and Symptom Management

Helping Patients with Advanced Cancer Live with Concerns About Eating: A Challenge for Palliative Care Professionals Jane Hopkinson, PhD, RGN, Jessica.

Cancer Symptom Clusters: A Validation Study

Associations Between Physical Activity and Quality of Life in Cancer Patients Receiving Palliative Care: A Pilot Survey Sonya S. Lowe, MD, MSc, Sharon.

Randomized Double-Blind Trial of Sublingual Atropine vs

Physical Activity Behaviors in Individuals with Multiple Sclerosis: Roles of Overall and Specific Symptoms, and Self-Efficacy Erin M. Snook, MS, Robert.

Efficacy and Safety of the Seven-Day Buprenorphine Transdermal System in Opioid- Naïve Patients with Moderate to Severe Chronic Low Back Pain: An Enriched,

Presentation transcript:

Analgesic and Sedative Effects of Melatonin in Temporomandibular Disorders: A Double-Blind, Randomized, Parallel-Group, Placebo-Controlled Study Liliane Pinto Vidor, DDS, MsH, Iraci L.S. Torres, PharmD, PhD, Izabel Cristina Custódio de Souza, PhD, Felipe Fregni, MD, PhD, Wolnei Caumo, MD, PhD Journal of Pain and Symptom Management Volume 46, Issue 3, Pages 422-432 (September 2013) DOI: 10.1016/j.jpainsymman.2012.08.019 Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 1 Flow diagram of study, including the number of patients at each study time point. SRQ=Self-Report Questionnaire; RDC/TMD=Research Diagnostic Criteria for Temporomandibular Disorders; VAS=Visual Analogue Scale. Journal of Pain and Symptom Management 2013 46, 422-432DOI: (10.1016/j.jpainsymman.2012.08.019) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 2 Mean pain levels (as assessed by VAS) at baseline week (W0), W1, W2, W3, and W4 in the two experimental groups. The error bars indicate standard error of the mean. Asterisks positioned above the bars indicate significant difference (P<0.05) at the time points. Asterisk (*) indicates differences between the placebo and melatonin treatment groups. All comparisons were performed by a mixed analysis of variance model, followed by the Bonferroni test for post hoc multiple comparisons. VAS=Visual Analogue Scale. Journal of Pain and Symptom Management 2013 46, 422-432DOI: (10.1016/j.jpainsymman.2012.08.019) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions

Fig. 3 The mean sleep quality from the previous night (as assessed by VASQS) at baseline week (W0), W1, W2, W3, and W4 in the two experimental groups. The error bars indicate standard error of the mean. Asterisks positioned above the bars indicate significant difference (P<0.05) at the various time points. Asterisk (*) indicates the differences between the placebo and melatonin treatment groups. All comparisons were performed using a mixed analysis of variance model, followed by the Bonferroni test for post hoc multiple comparisons. VASQS=Visual Analogue Sleep Quality Scale. Journal of Pain and Symptom Management 2013 46, 422-432DOI: (10.1016/j.jpainsymman.2012.08.019) Copyright © 2013 U.S. Cancer Pain Relief Committee Terms and Conditions