Confocal Laser Endomicroscopy for In Vivo Diagnosis of Early Squamous Cell Carcinoma in the Esophagus  Oliver Pech, Thomas Rabenstein, Hendrik Manner, Maria C. Petrone, Jürgen Pohl, Michael Vieth, Manfred Stolte, Christian Ell  Clinical Gastroenterology and Hepatology  Volume 6, Issue 1, Pages 89-94 (January 2008) DOI: 10.1016/j.cgh.2007.10.013 Copyright © 2008 AGA Institute Terms and Conditions

Figure 1 Confocal image of regular squamous epithelium. Clinical Gastroenterology and Hepatology 2008 6, 89-94DOI: (10.1016/j.cgh.2007.10.013) Copyright © 2008 AGA Institute Terms and Conditions

Figure 2 (A) Confocal image of squamous cell neoplasia with inhomogeneous cells, with irregular and unclear border demarcation. (B) Confocal image of squamous cell neoplasia, showing irregular elongated capillaries. (C) Confocal image of squamous cell neoplasia, with capillary leakage. Clinical Gastroenterology and Hepatology 2008 6, 89-94DOI: (10.1016/j.cgh.2007.10.013) Copyright © 2008 AGA Institute Terms and Conditions

Figure 3 (A) Confocal image of hyperplastic squamous epithelium with foci of dark cells with different sizes and irregular architecture falsely misinterpreted as a neoplastic lesion. (B) Corresponding histologic image (H&E staining; luminal [left side]) with elongated papillaries, partially distorted squamous epithelium with enlarged cells (black arrows), and dilatation of intercellular spaces (white arrows). Desquamation of the superficial cells is seen as a possible sign of regeneration. Clinical Gastroenterology and Hepatology 2008 6, 89-94DOI: (10.1016/j.cgh.2007.10.013) Copyright © 2008 AGA Institute Terms and Conditions