Monocyte-Plasmablast Crosstalk during Dengue

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Monocyte-Plasmablast Crosstalk during Dengue Angela M. Green, Eva Harris Cell Host & Microbe Volume 16, Issue 1, Pages 7-9 (July 2014) DOI: 10.1016/j.chom.2014.06.011 Copyright © 2014 Elsevier Inc. Terms and Conditions

Figure 1 Identification of CD14+CD16+ Monocytes Involved in Plamablast Differentiation CD14+CD16+ monocytes increase in humans and nonhuman primates following DENV infection. This monocyte population migrates to the lymph node and expresses markers of subcapsular sinus macrophages, which are capable of activating antigen-specific B cells. CD14+CD16+ monocytes stimulate plasmablast formation in vitro, driven by BAFF, APRIL, and IL-10. Illustrated by Sara Watson. Cell Host & Microbe 2014 16, 7-9DOI: (10.1016/j.chom.2014.06.011) Copyright © 2014 Elsevier Inc. Terms and Conditions