Angiogenesis Inhibitors Supplementary Figure 1 A Supplementary Figure 2 A B Angiogenesis Inhibitors EpI Screen
SKOV3 DMSO Vorinostat Mocetinostat Entinostat 500 nM 5 mM Supplementary Figure 3 SKOV3 DMSO Vorinostat Mocetinostat Entinostat 2.7 5.7 6.1 4.7 500 nM 1.0 1.7 4.1 3.1 92.1 87.5 85.6 87.2 5.0 11.2 12.7 8.3 5 mM 0.7 7.3 11.3 6.9 88.5 74.8 71.3 79.1
T24 DMSO Vorinostat Mocetinostat Entinostat 500 nM 5 mM Supplementary Figure 3 (cont’d) T24 DMSO Vorinostat Mocetinostat Entinostat 10.2 9.9 23.3 18.6 500 nM 2.6 2.8 8.1 4.7 83.0 80.9 65.0 71.3 6.6 15.8 16.0 12.7 5 mM 1.6 11.0 33.5 14.5 85.8 68.8 48.2 68.5
Supplementary Figure 4 A B C 24 96 (Hr) DMSO or HDACi Treatment 24 96 (Hr) DMSO or HDACi Treatment Cell Plating MTS Assay 48 Taxol B C