Supplementary Figure S1

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Supplementary Figure S1 Anterior and cranial areas of the pancreas near the duodenum Areas of the pancreas near the ampulla of Vater Quantitative measurement as the percentage area infiltrated by adipocytes relative to the total calculated using the WinROOF image analysis software package Yes No 2. Selection of the total area of pancreas on the section 1. Selection of normal pancreas of the sample Exclusion of the sample Selection of the boundary between pancreas and peripancreatic adipose tissue by existence of islets when pancreatic parenchyma is severely replaced by fat or fibrous tissue 3. Measurement of FI on the section

Fatty pancreas Pancreatic cancer Supplementary Figure S2 Fatty pancreas Pancreatic cancer Association of fatty pancreas with pancreatic cancer Obesity (High BMI)