BL4010 Final Exam Fall 2006 Name______________________ 1. Describe the phenomenon depicted in the figure below and discuss the driving forces and energetic barriers. Use text, figures, graphs, as needed.

BL4010 Final Exam Fall 2006 Name______________________ 2. Two classes of ionophore antibiotics are shown. Describe the purpose and function of each of the two types.

Name______________________ BL4010 Final Exam Fall 2006 Name______________________ Describe the following terms. Use diagrams if needed. a) Passive Diffusion b) Facilitated Diffusion c) Active Transport d) Amphiphilic helix

BL4010 Final Exam Fall 2006 Name______________________ 4. The signaling pathway for insulin secretion is shown. Describe the signaling events and the different elements in the pathway.

BL4010 Final Exam Fall 2006 Name______________________ 5. What is a signaling pathway and what are its minimal components? Describe and diagram a generic signaling model.

BL4010 Final Exam Fall 2006 Name______________________ 6. The signaling pathway for the ras oncogene is shown below. Use this example to discuss the complexity of signaling pathways, regulation of cellular processes and the consequences of mutation on pathway components.