Lucio Lombardo, Monica Foti, Olga Ruggia, Andrea Chiecchio 

Slides:



Advertisements
Similar presentations
Wai–Kit Lo, Walter W. Chan  Clinical Gastroenterology and Hepatology 
Advertisements

Small Intestinal Bacterial Overgrowth in Rosacea: Clinical Effectiveness of Its Eradication  Andrea Parodi, Stefania Paolino, Alfredo Greco, Francesco.
Lucio Lombardo, Monica Foti, Olga Ruggia, Andrea Chiecchio 
Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: Systematic Review and Meta-analysis  Alexander C. Ford, Brennan M.R. Spiegel, Nicholas.
Proton Pump Inhibitors and Acute Interstitial Nephritis
The Role of Psychosocial Care in Adapting to Health Care Reform
Gastrointestinal Symptoms in 342 Patients With Fabry Disease: Prevalence and Response to Enzyme Replacement Therapy  Bjoern Hoffmann, Martin Schwarz,
Abnormal Liver Tests and Fatty Liver on Ultrasound
Thrombocytopenia With Abnormal Liver Function Tests
CLINICAL SIGNIFICANCE AND
J. Enrique Domínguez–Muñoz  Clinical Gastroenterology and Hepatology 
Pancreas and Liver Injury Are Associated in Individuals With Increased Alcohol Consumption  Andrea Pace, Andreas de Weerth, Marc Berna, Katharina Hillbricht,
Prevalence, Characteristics, and Impact of Bloating Symptoms in Patients With Irritable Bowel Syndrome  Yehuda Ringel, Rachel E. Williams, Linda Kalilani,
Pichamol Jirapinyo, Christopher C. Thompson 
Proton Pump Inhibitors for Gastroduodenal Damage Related to Nonsteroidal Anti- inflammatory Drugs or Aspirin: Twelve Important Questions for Clinical Practice 
Gauree Gupta, Ebbing Lautenbach, James D. Lewis 
Celiac Disease and Persistent Symptoms
David L. McCollum, J. Martin Rodriguez 
Right Upper Quadrant Pain and a Normal Abdominal Ultrasound
Prevalence of Irritable Bowel Syndrome–type Symptoms in Patients With Celiac Disease: A Meta-analysis  Anita Sainsbury, David S. Sanders, Alexander C.
A Model to Determine Absolute Risk for Esophageal Adenocarcinoma
Small Intestinal Bacterial Overgrowth in Rosacea: Clinical Effectiveness of Its Eradication  Andrea Parodi, Stefania Paolino, Alfredo Greco, Francesco.
Eamonn M.M. Quigley  Clinical Gastroenterology and Hepatology 
Amnon Sonnenberg, MD, MSc, Brent Y. Lee, MD 
Should the Reflex Be Reflux
Small Intestinal Bacterial Overgrowth in Irritable Bowel Syndrome: Systematic Review and Meta-analysis  Alexander C. Ford, Brennan M.R. Spiegel, Nicholas.
Maintenance of Heartburn Relief After Step-Down From Twice-Daily Proton Pump Inhibitor to Once-Daily Dexlansoprazole Modified Release  Ronnie Fass, John.
Miles Basil, Anita Pudusseri, Robert Lowe 
Questioning the Bacterial Overgrowth Hypothesis of Irritable Bowel Syndrome: An Epidemiologic and Evolutionary Perspective  Brennan M.R. Spiegel  Clinical.
Endoscopic Therapy for Barrett's Esophagus
Traveling Internationally: Avoiding and Treating Travelers' Diarrhea
AGA Clinical Practice Update on Functional Gastrointestinal Symptoms in Patients With Inflammatory Bowel Disease: Expert Review  Jean-Frederic Colombel,
Patrick Hoversten, Fouad Otaki, David A. Katzka 
Leon P. McLean, Jonathan S. Chun, Raymond K. Cross 
Kasaya Tantiphlachiva, Priyanka Rao, Ashok Attaluri, Satish S.C. Rao 
Many Patients Continue Using Proton Pump Inhibitors After Negative Results From Tests for Reflux Disease  Andrew J. Gawron, Jami Rothe, Angela J. Fought,
Abnormal Liver Tests and Fatty Liver on Ultrasound
William D. Leslie  Clinical Gastroenterology and Hepatology 
Neeraj Sharma, Amit Agrawal, Janice Freeman, Marcelo F
New Models of Gastroenterology Practice
Unusual Cause of Abdominal Pain: Peutz–Jeghers Syndrome
George N. Ioannou, Meaghan F. Splan, Noel S. Weiss, George B
David H. Bruining, William J. Sandborn 
Chronic Abdominal Pain and Depressive Symptoms: Analysis of the National Longitudinal Study of Adolescent Health  Nader N. Youssef, Katherine Atienza,
Peter Bytzer  Clinical Gastroenterology and Hepatology 
Wai–Kit Lo, Walter W. Chan  Clinical Gastroenterology and Hepatology 
Kamal V. Patel, Rishi M. Goel, Terry Wong 
Rebecca M. Lovell, Alexander C. Ford 
Systematic Review: Patterns of Proton Pump Inhibitor Use and Adherence in Gastroesophageal Reflux Disease  A. Pali S. Hungin, Catherine Hill, Michael.
Gastrointestinal Symptoms in 342 Patients With Fabry Disease: Prevalence and Response to Enzyme Replacement Therapy  Bjoern Hoffmann, Martin Schwarz,
Lia C. Kaufman, Jana G. Hashash 
Effects of Different Coping Strategies on Physical and Mental Health of Patients With Irritable Bowel Syndrome  Lilian Dindo, PhD  Clinical Gastroenterology.
Issue Highlights Clinical Gastroenterology and Hepatology
Systematic Review and Meta-analysis of the Prevalence of Irritable Bowel Syndrome in Individuals With Dyspepsia  Alexander C. Ford, Avantika Marwaha,
Medical Malpractice in Gastroenterology
Etiologies and Predictors of Diagnosis in Nonresponsive Celiac Disease
Bacterial Overgrowth in Intestinal Lipomatosis With Pandiverticulosis
Thrombocytopenia With Abnormal Liver Function Tests
A 27-Year-Old Woman With Constipation: Diagnosis and Treatment
Angad S. Uberoi, Asif Rashid, Manoop S. Bhutani 
Patrick Yachimski, William P. Puricelli, Norman S. Nishioka 
Coagulation in Liver Disease: A Guide for the Clinician
Issue Highlights Clinical Gastroenterology and Hepatology
Erick Alayo, Bashar Attar, Benjamin Go 
Neeraj Sharma, Amit Agrawal, Janice Freeman, Marcelo F
Medical Therapy for Refractory Pediatric Crohn’s Disease
Challenges of NIH Funding for Young Investigators: How the AGA Is Filling the Gap via the AGA Research Foundation  Timothy C. Wang, Rhonda F. Souza  Clinical.
Issue Highlights Clinical Gastroenterology and Hepatology
The Role of Psychosocial Care in Adapting to Health Care Reform
Choosing Wisely and the Perceived Drivers of Endoscopy Use
Presentation transcript:

Increased Incidence of Small Intestinal Bacterial Overgrowth During Proton Pump Inhibitor Therapy  Lucio Lombardo, Monica Foti, Olga Ruggia, Andrea Chiecchio  Clinical Gastroenterology and Hepatology  Volume 8, Issue 6, Pages 504-508 (June 2010) DOI: 10.1016/j.cgh.2009.12.022 Copyright © 2010 AGA Institute Terms and Conditions

Figure 1 Prevalence of small intestinal bacterial overgrowth (mean value ± standard deviation), as assessed by glucose hydrogen breath test. Clinical Gastroenterology and Hepatology 2010 8, 504-508DOI: (10.1016/j.cgh.2009.12.022) Copyright © 2010 AGA Institute Terms and Conditions

Figure 2 Age distribution (mean value ± standard deviation) in PPI and IBS GHBT-positive patients. Clinical Gastroenterology and Hepatology 2010 8, 504-508DOI: (10.1016/j.cgh.2009.12.022) Copyright © 2010 AGA Institute Terms and Conditions

Figure 3 Prevalence of small intestinal bacterial overgrowth (mean value ± standard deviation) in PPI-treated patients according to the duration of therapy. Clinical Gastroenterology and Hepatology 2010 8, 504-508DOI: (10.1016/j.cgh.2009.12.022) Copyright © 2010 AGA Institute Terms and Conditions

Figure 4 Severity of symptoms (mean value ± standard deviation) assessed by symptom index score in different classes of duration of PPI therapy (months). Clinical Gastroenterology and Hepatology 2010 8, 504-508DOI: (10.1016/j.cgh.2009.12.022) Copyright © 2010 AGA Institute Terms and Conditions

Figure 5 Types of SIBO-related symptoms in PPI and IBS groups. B, bloating; C, constipation; D, diarrhea; MA, macrocytic/megaloblastic anemia (hemoglobin <11 g/dL; mean globular volume >98 fmol; red blood cell count <4,000,000/μL); P, lower abdominal pain (of any degree during the last month); WL, weight loss (>10% during the last 6 months). Clinical Gastroenterology and Hepatology 2010 8, 504-508DOI: (10.1016/j.cgh.2009.12.022) Copyright © 2010 AGA Institute Terms and Conditions